<Tr> <Td_colspan="2"> Grey's Anatomy character </Td> </Tr> <Tr> <Td_colspan="2"> The Season 6 Promotional Photo of Katherine Heigl as Dr. Izzie Stevens </Td> </Tr> <Tr> <Th> First appearance </Th> <Td> "A Hard Day's Night" (1.01) March 27, 2005 </Td> </Tr> <Tr> <Th> Last appearance </Th> <Td> "I Like You So Much Better When You're Naked" (6.12) January 21, 2010 </Td> </Tr>

When does the first character die in grey's anatomy