<P> "My mind was, that a dogma was an idea for which there was no reasonable evidence . You see?!" And Crick gave a roar of delight . "I just didn't know what dogma meant . And I could just as well have called it the' Central Hypothesis,' or--you know . Which is what I meant to say . Dogma was just a catch phrase ." </P> <P> The Weismann barrier, proposed by August Weismann in 1892, distinguishes between the "immortal" germ cell lineages (the germ plasm) which produce gametes and the "disposable" somatic cells . Hereditary information moves only from germline cells to somatic cells (that is, somatic mutations are not inherited). This, before the discovery of the role or structure of DNA, does not predict the central dogma, but does anticipate its gene - centric view of life, albeit in non-molecular terms . </P>

According to the central dogma of biology the flow of genetic information in a cell is from