<Ul> <Li> Tom Wilkinson as Dr. Howard Mierzwiak: Howard runs Lacuna . Before the film's events, he had an affair with Mary, which ended with the relationship's erasure from her mind . Wilkinson reportedly did not enjoy the shooting of the film and frequently disagreed with Gondry . </Li> </Ul> <Li> Tom Wilkinson as Dr. Howard Mierzwiak: Howard runs Lacuna . Before the film's events, he had an affair with Mary, which ended with the relationship's erasure from her mind . Wilkinson reportedly did not enjoy the shooting of the film and frequently disagreed with Gondry . </Li> <Ul> <Li> Jane Adams as Carrie Eakin: Joel's friend . She is in a troubled relationship with Rob . </Li> </Ul> <Li> Jane Adams as Carrie Eakin: Joel's friend . She is in a troubled relationship with Rob . </Li>

What is the theme of the movie eternal sunshine of the spotless mind