<Ul> <Li> See Autoradiograph of intact replicating chromosome of E. coli (1) </Li> </Ul> <Li> See Autoradiograph of intact replicating chromosome of E. coli (1) </Li> <P> As described above, bacterial chromosomal replication occurs in a bidirectional manner . This was first demonstrated by specifically labelling replicating bacterial chromosomes with radioactive isotopes . The regions of DNA undergoing replication during the experiment were then visualized by using autoradiography and examining the developed film microscopically . This allowed the researchers to see where replication was taking place . The first conclusive observations of bidirectional replication was from studies of B. subtilis . Shortly after, the E. coli chromosome was also shown to replicate bidirectionally . </P> <Ul> <Li> See Figure 4 of D.M. Prescott, and P.L. Kuempel (1972): A grain track produced by an E. coli chromosome from cells labeled for 19 min with (3H) thymine, followed by labelingfor 2.5 min with (3H) thymine and (' H) thymidine. (2). </Li> </Ul>

Where is the chromosomal dna of a bacterium found