<P> In 1965, lardy introduced the term "cytosol", later redefined to refer to the liquid inside cell . </P> <P> By the time Huxley wrote, a long - standing debate was largely settled over the fundamental unit of life: was it the cell or was it protoplasm? By the late 1860s, the debate was largely settled in favor of protoplasm . The cell was a container for protoplasm, the fundamental and universal material substance of life . Huxley's principal contribution was to establish protoplasm as incompatible with a vitalistic theory of life . Attempts to investigate the origin of life through the creation of synthetic "protoplasm" in the laboratory were not successful . </P> <P> The idea that protoplasm of eukaryotes is simply divisible into a ground substance called "cytoplasm" and a structural body called the cell nucleus reflects the more primitive knowledge of cell structure that preceded the development of electron microscopy, when it seemed that cytoplasm was a homogeneous fluid and the existence of most sub-cellular compartments, or how cells maintain their shape, was unknown . Today, it is known that the cell contents are structurally very complex and contain multiple organelles . </P> <Table> <Tr> <Td> </Td> <Td> This section does not cite any sources . Please help improve this section by adding citations to reliable sources . Unsourced material may be challenged and removed . (August 2016) (Learn how and when to remove this template message) </Td> </Tr> </Table>

What is the fluid substance of cell known as