<Tr> <Th> MeSH </Th> <Td> D019161 </Td> </Tr> <Tr> <Td_colspan="2"> In Wikidata </Td> </Tr> <P> Statins, also known as HMG - CoA reductase inhibitors, are a class of lipid - lowering medications . Statins have been found to reduce cardiovascular disease and mortality in those who are at high risk of cardiovascular disease . The evidence is strong that statins are effective for treating cardiovascular disease in the early stages of the disease (secondary prevention) and in those at elevated risk but without cardiovascular disease (primary prevention). </P> <P> Side effects of statins include muscle pain, increased risk of diabetes mellitus, and abnormalities in liver enzyme tests . Additionally, they have rare but severe adverse effects, particularly muscle damage . They inhibit the enzyme HMG - CoA reductase which plays a central role in the production of cholesterol . High cholesterol levels have been associated with cardiovascular disease . </P>

Statins is the name given to a group of which type of drugs