<P> The withdrawal reflex (nociceptive flexion reflex or flexor withdrawal reflex) is a spinal reflex intended to protect the body from damaging stimuli . Spinal reflexes are often monosynaptic and are mediated by a simple reflex arc . A withdrawal reflex is mediated by a polysynaptic reflex resulting in the stimulation of many motor neurons in order to give a quick response . </P> <P> When a person touches a hot object and withdraws their hand from it without actively thinking about it, the heat stimulates temperature and pain receptors in the skin, triggering a sensory impulse that travels to the central nervous system . The sensory neuron then synapses with interneurons that connect to motor neurons . Some of these send motor impulses to the flexors that lead to the muscles in the arm to contract, while some motor neurons send inhibitory impulses to the extensors so flexion is not inhibited . This is referred to as reciprocal innervation . </P> <P> The withdrawal reflex in the leg can be examined and measured, using an electromyogram to monitor the muscle activity in the upper leg (biceps femoris) while applying increasing electrical stimulation to the lower leg (sural nerve) on the same side of the body . The stimulus intensity at which the reflex is evoked is often the intensity at which the subject reports the onset of pain, and the strength of the withdrawal reflex is correlated with the strength of the pain experienced . </P>

Correct order for the pathway in a flexion withdrawal reflex arc
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