<P> Despicable Me 2 is a 2013 American 3D computer - animated comedy film and the sequel to the 2010 animated film Despicable Me . Produced by Illumination Entertainment for Universal Pictures and animated by Illumination Mac Guff, the film was directed by Pierre Coffin and Chris Renaud, and written by Cinco Paul and Ken Daurio . Steve Carell, Russell Brand, Miranda Cosgrove, Elsie Fisher, and Dana Gaier reprise their roles as Gru, Dr. Nefario, Margo, Agnes, and Edith respectively . Kristen Wiig, who played Miss Hattie in the first film, voices agent Lucy Wilde, while Ken Jeong, who played the Talk Show Host, voices Floyd Eagle - san . New cast members include Benjamin Bratt as Eduardo "El Macho" Pérez and Steve Coogan as Silas Ramsbottom, head of the fictional Anti-Villain League (AVL). </P> <P> Despicable Me 2 premiered on June 5, 2013 in Australia and was released in the United States on July 3, 2013 . The film received mostly positive reviews from critics, and was nominated for Academy Award for Best Animated Feature and for Academy Award for Best Original Song (for "Happy"), losing both to Walt Disney Animation Studios' Frozen . Grossing over $970.8 million worldwide against its budget of $76 million, the film became the second - highest - grossing animated film of 2013 and the third highest - grossing film of 2013 . It is also the most profitable film in the 101 - year history of Universal Studios . A spinoff / prequel film, Minions, focusing on the little yellow henchmen before they met Gru, was released on July 10, 2015 . A sequel, Despicable Me 3, was released on June 30, 2017 . </P> <P> A mysterious vehicle using a huge magnet steals a highly potent mutagen known as PX - 41 from a secret laboratory in the Arctic Circle . The Anti-Villain League (AVL), headed by Silas Ramsbottom, tries to recruit former supervillain Gru to track down those responsible and recover the mutagen, but Gru refuses, claiming that he is now a legitimate businessman as well as the devoted father of Margo, Edith, and Agnes . Dr. Nefario, Gru's friend and assistant, longs to go back to villainy and leaves Gru for new employment . Gru reluctantly agrees to investigate the theft, and is partnered with undercover AVL agent Lucy Wilde . </P> <P> The pair begin their search in the Paradise Shopping Mall, disguised as bakery employees . Gru immediately comes to suspect Mexican restaurant owner, Eduardo Pérez, of being the infamous "El Macho", a legendary supervillain who supposedly died by riding a shark into the mouth of an active volcano with 250 pounds of dynamite strapped to his chest . Gru and Lucy break into Eduardo's restaurant at night, but find no proof . Meanwhile, Agnes, confiding in her dream to one day have a mother, believes that Gru will fall in love with Lucy, though Gru states that his relationship with Lucy is professional . </P>

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