<Li> Centronuclear myopathy; where cell nuclei are abnormally located in skeletal muscle cells . In CNM the nuclei are located at a position in the center of the cell, instead of their normal location at the periphery . </Li> <Li> Charcot--Marie--Tooth disease (CMTX2 - 3); disorder of nerves (neuropathy) that is characterized by loss of muscle tissue and touch sensation, predominantly in the feet and legs but also in the hands and arms in the advanced stages of disease . </Li> <Li> Coffin--Lowry syndrome; severe mental retardation sometimes associated with abnormalities of growth, cardiac abnormalities, kyphoscoliosis as well as auditory and visual abnormalities . </Li> <Li> Fabry disease; A lysosomal storage disease causing anhidrosis, fatigue, angiokeratomas, burning extremity pain and ocular involvement . </Li>

What does it mean to be homozygous for a certain trait