<Tr> <Th> Treatment </Th> <Td> Thiamine supplementation </Td> </Tr> <Tr> <Th> Frequency </Th> <Td> Rare (US) </Td> </Tr> <P> Thiamine deficiency is a medical condition of low levels of thiamine (vitamin B1). A severe and chronic form is known as beriberi . There are two main types in adults: wet beriberi, and dry beriberi . Wet beriberi affects the cardiovascular system resulting in a fast heart rate, shortness of breath, and leg swelling . Dry beriberi affects the nervous system resulting in numbness of the hands and feet, confusion, trouble moving the legs, and pain . A form with loss of appetite and constipation may also occur . Another type, acute beriberi, is found mostly in babies and presents with loss of appetite, vomiting, lactic acidosis, changes in heart rate, and enlargement of the heart . </P> <P> Risk factors include a diet of mostly white rice, as well as alcoholism, dialysis, chronic diarrhea, and taking high doses of diuretics . Rarely it may be due to a genetic condition which results in difficulties absorbing thiamine found in food . Wernicke encephalopathy and Korsakoff syndrome are forms of dry beriberi . Diagnosis is based on symptoms, low levels of thiamine in the urine, high blood lactate, and improvement with treatment . </P>

Deficiency of which vitamin causes beri beri disease
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