<P> She moved to New York City at the age of 18 to study theatre at New York University's Tisch School of the Arts . While living in New York, she became involved in the club scene (known there only as "Lisa E") and caused enough of a stir in the community to be dubbed New York City's "Queen of the Night" by writer and fellow celebutant James St. James, who briefly refers to Edelstein in his 1999 book Disco Bloodbath . </P> <P> After being dubbed a "celebutante" by The New York Times magazine during her club kid days, Edelstein used her new - found celebrity to write, compose and star in an original musical called Positive Me in response to the growing AIDS crisis of the 1980s . The play, performed at La MaMa Experimental Theatre Club in New York City, received many accolades . After a regrettable experience hosting Awake on the Wild Side for MTV in 1990, she appeared for a few seconds as a backstage make - up artist in the Jim Morrison biography The Doors followed by guest roles on several popular comedies, including Mad About You, Wings, and The Larry Sanders Show . On Sports Night, she played a sports reporter who claimed to be a former lover of Josh Charles's character whom he did not remember . On Seinfeld, she played George Costanza's frustrated girlfriend, the "Risotto Girl". </P> <P> Bigger roles in TV dramas soon followed, among them the lesbian sister on ABC's Relativity (1996); a high - priced call girl turned Rob Lowe's date on The West Wing (1999); an assigned male at birth (AMAB) transgender woman on Ally McBeal (2000); and Ben Covington's (Scott Speedman) girlfriend on Felicity (2001). She also continued to land guest - star spots on such shows as ER, Frasier, Just Shoot Me!, Without a Trace, and Judging Amy, as well as small parts in the films What Women Want, Keeping the Faith, As Good as It Gets, and Daddy Day Care . </P> <P> From 2004 to 2011, she portrayed her biggest and most notable role to date, Dr. Lisa Cuddy, the Dean of Medicine at Princeton - Plainsboro Teaching Hospital and frequent adversary, friend, and eventual girlfriend of title character Gregory House (Hugh Laurie) on Fox's TV series House . Edelstein has often spoken fondly of her experiences on the show and fellow cast and crew, especially her friendship and strong working relationship with Laurie . </P>

Who plays the call girl in west wing
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