<Tr> <Td_colspan="2"> * Annual estimated passenger usage based on sales of tickets in stated financial year (s) which end or originate at Manchester Piccadilly from Office of Rail and Road statistics . Methodology may vary year on year . </Td> </Tr> <Tr> <Td_colspan="2"> UK Railways portal </Td> </Tr> <P> Manchester Piccadilly is the principal railway station in Manchester, England . Opened as Store Street in 1842, it was renamed Manchester London Road in 1847 and Manchester Piccadilly in 1960 . Located to the south - eastern side of Manchester city centre, it hosts intercity and cross-country services to national destinations including London Euston, Birmingham, Bristol, Southampton, Wales and Scotland, and local and regional services to destinations in Northern England including Liverpool, Leeds, Sheffield, Newcastle and York . It is one of 19 major stations managed by Network Rail . </P> <P> The station has twelve terminal platforms in the train shed and two through platforms to the south of it . Piccadilly is also a major interchange with the Metrolink light rail system with two tram platforms in its undercroft . </P>

What is the main train station in manchester called