<P> The rogues gallery of Spider - Man has garnered many positive reviews and has been considered as one of the greatest rogues galleries of all time by many alongside Batman's rogues gallery . </P> <P> The majority of supervillains depicted in Spider - Man comics first appeared in The Amazing Spider - Man, while some first appeared in spinoff comics such as The Spectacular Spider - Man and Marvel Team - Up and other titles . </P> <P> Most of the supervillains of Spider - Man would be introduced in The Amazing Spider - Man comic book starting with the Chameleon . The early villains would be introduced in the 1960s in the Silver Age of Comic Books, and created by Stan Lee and Steve Ditko . John Romita, Sr. replaced Ditko starting with the Rhino . Gerry Conway later replaced Stan Lee and helped create new adversaries for the web - slinger and also helped pave the way to the Bronze Age of Comic Books with the death of Spider - Man's long time romantic interest, Gwen Stacy . Many collaborators would soon take over The Amazing Spider - Man title . One of the more popular examples included Todd McFarlane's Venom in the Modern Age of Comic Books . </P> <P> Note: Alter ego characters who are the most high profile in the supervillain alias but have shared that alias with others are in bold . Alter egos listed having N / A use their real name as the supervillain name . In chronological order . </P>

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