<P> The oldest known mosquito with an anatomy similar to modern species was found in 79 - million - year - old Canadian amber from the Cretaceous . An older sister species with more primitive features was found in Burmese amber that is 90 to 100 million years old . Two mosquito fossils have been found that show very little morphological change in modern mosquitoes against their counterpart from 46 million years ago . These fossils are also the oldest ever found to have blood preserved within their abdomens . Despite no fossils being found earlier than the Cretaceous, recent studies suggest that the earliest divergence of mosquitoes between the lineages leading to Anophelinae and Culicinae occurred 226 million years ago . </P> <P> The Old and New World Anopheles species are believed to have subsequently diverged about 95 million years ago . </P> <P> The mosquito Anopheles gambiae is currently undergoing speciation into the M (opti) and S (avanah) molecular forms . Consequently, some pesticides that work on the M form no longer work on the S form . Over 3,500 species of the Culicidae have already been described . They are generally divided into two subfamilies which in turn comprise some 43 genera . These figures are subject to continual change, as more species are discovered, and as DNA studies compel rearrangement of the taxonomy of the family . The two main subfamilies are the Anophelinae and Culicinae, with their genera as shown in the subsection below . The distinction is of great practical importance because the two subfamilies tend to differ in their significance as vectors of different classes of diseases . Roughly speaking, arboviral diseases such as yellow fever and dengue fever tend to be transmitted by Culicine species, not necessarily in the genus Culex . Some transmit various species of avian malaria, but it is not clear that they ever transmit any form of human malaria . Some species do however transmit various forms of filariasis, much as many Simuliidae do . </P> <P> Anopheline mosquitoes, again not necessarily in the genus Anopheles, sometimes bear pathogenic arboviruses, but it is not yet clear that they ever transmit them as effective vectors . However, all the most important vectors of human malaria are Anopheline . </P>

How many different species of mosquitoes are there