<Li> In 2012 in Alabama, United States there was an outbreak of an unusual type of the disease . It occurred in a season when it is not usually seen and affected teenagers and older adults . There were some hospitalizations due to the disease but no reported deaths . </Li> <Li> In 2012 in Cambodia, 52 of 59 reviewed cases of children reportedly dead (as of July 9, 2012) due to a mysterious disease were diagnosed to be caused by a virulent form of HFMD . Although a significant degree of uncertainty exists with reference to the diagnosis, the WHO report states, "Based on the latest laboratory results, a significant proportion of the samples tested positive for enterovirus 71 (EV - 71), which causes hand foot and mouth disease (HFMD). The EV - 71 virus has been known to generally cause severe complications amongst some patients ." </Li> <Li> HFMD infected 1,520,274 people with up to 431 deaths reported at the end of July in 2012 in China . </Li> <Li> The governorate of Daraa in Syria reported over 200 cases of HFMD there in early 2015 . These were due to the central Syrian government denying the region water chlorination . </Li>

Where did hand foot and mouth come from