<Dl> <Dd>--Preceding unsigned comment added by Lynne Mee (talk contribs) 20: 46, 9 November 2006 </Dd> </Dl> <Dd>--Preceding unsigned comment added by Lynne Mee (talk contribs) 20: 46, 9 November 2006 </Dd> <Dl> <Dd> As the article already indicates, the half - life of the drug in the body is 36 - 54 hours . So 1 / 2 the amount remains in the body at around 2 days, 1 / 4 by about 4 days, and by 1 week under 10% left . However remember that this tail - off level will be from the final very low dosage that you take . Secondly is the issue of steroid action on you body - this does not in fact tail - off to zero (one hopes). High doses of steroids suppress the natural production of the body's own cortisone and a large part of having to slowly reduce oral steroid medication is to allow the body's own production to restart . Hence patients on high dose steroids are warned not to stop their medication abruptly else they risk having no corticosteroid activity in their body, which may result in the medical emergency of Addisonian crisis . So once the dose & effectiveness of dexamethasone is slowly dropped below a minimum level, you own body restarts making its own weaker low - potency steroid necessary for normal health . Hence at the point that you finally discontinue the dexamethasone, its dosage and hence effectiveness will already have been dropped below the suppressive physiological level and your body will be making up the difference . The practical short answer to you question is therefore that at the point you stop the dexamethasone, it will already be at an insignificant dose as your body's own normal steroid production will be back in operation . </Dd> </Dl> <Dd> As the article already indicates, the half - life of the drug in the body is 36 - 54 hours . So 1 / 2 the amount remains in the body at around 2 days, 1 / 4 by about 4 days, and by 1 week under 10% left . However remember that this tail - off level will be from the final very low dosage that you take . Secondly is the issue of steroid action on you body - this does not in fact tail - off to zero (one hopes). High doses of steroids suppress the natural production of the body's own cortisone and a large part of having to slowly reduce oral steroid medication is to allow the body's own production to restart . Hence patients on high dose steroids are warned not to stop their medication abruptly else they risk having no corticosteroid activity in their body, which may result in the medical emergency of Addisonian crisis . So once the dose & effectiveness of dexamethasone is slowly dropped below a minimum level, you own body restarts making its own weaker low - potency steroid necessary for normal health . Hence at the point that you finally discontinue the dexamethasone, its dosage and hence effectiveness will already have been dropped below the suppressive physiological level and your body will be making up the difference . The practical short answer to you question is therefore that at the point you stop the dexamethasone, it will already be at an insignificant dose as your body's own normal steroid production will be back in operation . </Dd>

How long to get decadron out of system
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