<Li> Leukemia is a group of cancers of the blood - forming tissues and cells . </Li> <Li> Non-cancerous overproduction of red cells (polycythemia vera) or platelets (essential thrombocytosis) may be premalignant . </Li> <Li> Myelodysplastic syndromes involve ineffective production of one or more cell lines . </Li> <Li> Disorders of coagulation <Ul> <Li> Hemophilia is a genetic illness that causes dysfunction in one of the blood's clotting mechanisms . This can allow otherwise inconsequential wounds to be life - threatening, but more commonly results in hemarthrosis, or bleeding into joint spaces, which can be crippling . </Li> <Li> Ineffective or insufficient platelets can also result in coagulopathy (bleeding disorders). </Li> <Li> Hypercoagulable state (thrombophilia) results from defects in regulation of platelet or clotting factor function, and can cause thrombosis . </Li> </Ul> </Li>

What is the composition of blood in human