<P> This list of tallest buildings in Detroit ranks skyscrapers and high rises in the U.S. city of Detroit, Michigan by height . The tallest skyscraper in Detroit is the 73 - story Detroit Marriott at the Renaissance Center, which rises 727 feet (222 m) along Detroit's International Riverfront . It is the tallest building in the state of Michigan, the 97th - tallest building in the United States, and the second tallest hotel building in the Western Hemisphere . Another famous skyscraper is One Detroit Center, which stands as the 2nd - tallest building in the city and the state . </P> <P> Detroit's history of skyscrapers began in 1889, with completion of the historic 10 - story Hammond Building--considered the city's first steel - framed skyscraper . The Qube in the Detroit Financial District now stands on this site . Detroit witnessed a massive building boom during the Roaring Twenties, resulting in the construction of many of the city's ornate skyscrapers, including the Penobscot, Guardian, Fisher, Buhl, Stott, and Broderick . One Woodward Avenue, which rises 430 feet (131 m), was the tallest building constructed in the city during the 1960s . Detroit is the site of eight skyscrapers at least 492 feet (150 m) in height and twenty - seven at least 327 feet (100 m) in height . Overall, the skyline of Detroit is ranked (based upon existing and under construction buildings over 492 feet (150 m)) third in the Midwestern United States (after Chicago and Minneapolis) and sixteenth in the United States, after New York City, Chicago, Miami, Houston, Los Angeles, Dallas, Atlanta, San Francisco, Boston, Las Vegas, Seattle, Philadelphia, Pittsburgh, Jersey City, and Minneapolis . </P>

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