<Tr> <Td> DNA Polymerase </Td> <Td> The enzyme responsible for catalyzing the addition of nucleotide substrates to DNA in the 5' to 3' direction during DNA replication . Also performs proof - reading and error correction . There exist many different types of DNA Polymerase, each of which perform different functions in different types of cells . </Td> </Tr> <Tr> <Td> DNA clamp </Td> <Td> A protein which prevents elongating DNA polymerases from dissociating from the DNA parent strand . </Td> </Tr> <Tr> <Td> Single - Strand Binding (SSB) Proteins </Td> <Td> Bind to ssDNA and prevent the DNA double helix from re-annealing after DNA helicase unwinds it, thus maintaining the strand separation, and facilitating the synthesis of the nascent strand . </Td> </Tr> <Tr> <Td> Topoisomerase </Td> <Td> Relaxes the DNA from its super-coiled nature . </Td> </Tr>

In which direction does dna replication take place