<P> Dyloject (diclofenac) 2 ml for IV and IM administration </P> <Li> <P> Sintofarm (diclofenac) for suppository administration </P> </Li> <P> Sintofarm (diclofenac) for suppository administration </P> <Ul> <Li> Hypersensitivity against diclofenac </Li> <Li> History of allergic reactions (bronchospasm, shock, rhinitis, urticaria) following the use of other NSAIDs such as aspirin </Li> <Li> Third - trimester pregnancy </Li> <Li> Active stomach and / or duodenal ulceration or gastrointestinal bleeding </Li> <Li> Inflammatory bowel disease such as Crohn's disease or ulcerative colitis </Li> <Li> Severe insufficiency of the heart (NYHA III / IV) </Li> <Li> Pain management in the setting of coronary artery bypass graft (CABG) surgery </Li> <Li> Severe liver insufficiency (Child - Pugh Class C) </Li> <Li> Severe renal insufficiency (creatinine clearance <30 ml / min) </Li> <Li> Caution in patients with pre-existing hepatic porphyria, as diclofenac may trigger attacks </Li> <Li> Caution in patients with severe, active bleeding such as cerebral hemorrhage </Li> <Li> NSAIDs in general should be avoided during dengue fever, as it induces (often severe) capillary leakage and subsequent heart failure . </Li> <Li> Caution in patients with fluid retention or heart failure </Li> <Li> Can lead to onset of new hypertension or worsening of pre-existing hypertension </Li> <Li> Can cause serious skin adverse events such as exfoliative dermatitis, Stevens - Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal </Li> </Ul>

Major and minor side effect of diclofenac sodium