<P> In combination with the Alternative pathway hemolytic assay ("AH50") it can indicate terminal pathway deficiencies (C3, C5 - C9; absence of hemolysis in both CH50 and AH50), classic pathway deficiencies (C1, C2, C4; absence of lysis in CH50) and alternative pathway deficiencies (Factor I, B, H, D, properdin; absence of lysis in AH50). </P> <P> Increased CH50 values may be seen in cancer or ulcerative colitis . Decreased CH50 values may be seen in cirrhosis or hepatitis or Systemic lupus erythematosus . </P>

What is the purpose of the ch50 assay