<Ul> <Li> Chad Michael Murray as Lucas Scott (21 episodes) </Li> <Li> James Lafferty as Nathan Scott (22 episodes) </Li> <Li> Hilarie Burton as Peyton Sawyer (22 episodes) </Li> <Li> Bethany Joy Galeotti as Haley James Scott (22 episodes) </Li> <Li> Paul Johansson as Dan Scott (20 episodes) </Li> <Li> Sophia Bush as Brooke Davis (22 episodes) </Li> <Li> Barbara Alyn Woods as Deb Scott (13 episodes) </Li> <Li> Lee Norris as Mouth McFadden (18 episodes) </Li> <Li> Barry Corbin as Whitey Durham (12 episodes) </Li> <Li> Craig Sheffer as Keith Scott (13 episodes) </Li> <Li> Moira Kelly as Karen Roe (20 episodes) </Li> </Ul> <Li> Chad Michael Murray as Lucas Scott (21 episodes) </Li> <Li> James Lafferty as Nathan Scott (22 episodes) </Li> <Li> Hilarie Burton as Peyton Sawyer (22 episodes) </Li>

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