<Tr> <Td_colspan="2"> (edit on Wikidata) </Td> </Tr> <P> Hypoproteinemia is a condition where there is an abnormally low level of protein in the blood . There are several causes that all result in edema once serum protein levels fall below a certain threshold . </P> <Ol> <Li> Nutritional hypoproteinemia is due to severe limitation of protein intake in the diet . An example of nutritional hypoproteinemia is Kwashiorkor, a type of protein energy malnutrition affecting young children . </Li> <Li> Malabsorption </Li> <Li> Liver disease can also cause hypoproteinemia by decreasing synthesis of plasma proteins like albumin . </Li> <Li> Renal disease like nephrotic syndrome can also result in hypoproteinemia because plasma proteins are lost in the urine . </Li> <Li> Sepsis (whole body infection)--macrophages activated in the liver and spleen secrete TNF - alpha into the bloodstream resulting in hypoproteinemia . </Li> </Ol> <Li> Nutritional hypoproteinemia is due to severe limitation of protein intake in the diet . An example of nutritional hypoproteinemia is Kwashiorkor, a type of protein energy malnutrition affecting young children . </Li>

Why there is accumulation of fluid in hypoproteinemia