<P> The diagnosis of MVP depends upon echocardiography, which uses ultrasound to visualize the mitral valve . The prevalence of MVP is estimated at 2--3% of the population . </P> <P> The condition was first described by John Brereton Barlow in 1966 . In consequence, it may also be referred to as Barlow's syndrome, and was subsequently termed mitral valve prolapse by J. Michael Criley . </P> <P> Upon auscultation of an individual with mitral valve prolapse, a mid-systolic click, followed by a late systolic murmur heard best at the apex is common . The length of the murmur signifies the time period over which blood is leaking back into the left atrium, known as regurgitation . A murmur that lasts throughout the whole of systole is known as a holo - systolic murmur . A murmur that is mid to late systolic, although typically associated with less regurgitation, can still be associated with significant hemodynamic consequences . </P> <P> In contrast to most other heart murmurs, the murmur of mitral valve prolapse is accentuated by standing and valsalva maneuver (earlier systolic click and longer murmur) and diminished with squatting (later systolic click and shorter murmur). The only other heart murmur that follows this pattern is the murmur of hypertrophic cardiomyopathy . A MVP murmur can be distinguished from a hypertrophic cardiomyopathy murmur by the presence of a mid-systolic click which is virtually diagnostic of MVP . The handgrip maneuver diminishes the murmur of an MVP and the murmur of hypertrophic cardiomyopathy . The handgrip maneuver also diminishes the duration of the murmur and delays the timing of the mid-systolic click . </P>

Where do you hear a mitral valve murmur
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