<Ul> <Li> </Li> <Li> The endemic variant (also called "African variant") most commonly occurs in children living in malaria endemic regions of the world (e.g., equatorial Africa, Brazil, and Papua New Guinea). Epstein - Barr virus (EBV) infection is found in nearly all patients . Chronic malaria is believed to reduce resistance to EBV, allowing it to take hold . The disease characteristically involves the jaw or other facial bone, distal ileum, cecum, ovaries, kidney, or breast . </Li> <Li> The sporadic type of Burkitt lymphoma (also known as "non-African") is the most common variant found in places where malaria is not holoendemic . The tumor cells have a similar appearance to the cancer cells of classical endemic Burkitt lymphoma . Sporadic lymphomas are rarely associated with the Epstein--Barr virus . Non-Hodgkin lymphoma, which includes Burkitt's, accounts for 30--50% of childhood lymphoma . The jaw is less commonly involved, compared to the endemic variant . The ileocecal region is the common site of involvement . </Li> <Li> Immunodeficiency - associated Burkitt lymphoma is usually associated with HIV infection or occurs in the setting of post-transplant patients who are taking immunosuppressive drugs . Burkitt lymphoma can be one of the diseases associated with the initial manifestation of AIDS . </Li> </Ul> <Li> The endemic variant (also called "African variant") most commonly occurs in children living in malaria endemic regions of the world (e.g., equatorial Africa, Brazil, and Papua New Guinea). Epstein - Barr virus (EBV) infection is found in nearly all patients . Chronic malaria is believed to reduce resistance to EBV, allowing it to take hold . The disease characteristically involves the jaw or other facial bone, distal ileum, cecum, ovaries, kidney, or breast . </Li> <Li> The sporadic type of Burkitt lymphoma (also known as "non-African") is the most common variant found in places where malaria is not holoendemic . The tumor cells have a similar appearance to the cancer cells of classical endemic Burkitt lymphoma . Sporadic lymphomas are rarely associated with the Epstein--Barr virus . Non-Hodgkin lymphoma, which includes Burkitt's, accounts for 30--50% of childhood lymphoma . The jaw is less commonly involved, compared to the endemic variant . The ileocecal region is the common site of involvement . </Li> <Li> Immunodeficiency - associated Burkitt lymphoma is usually associated with HIV infection or occurs in the setting of post-transplant patients who are taking immunosuppressive drugs . Burkitt lymphoma can be one of the diseases associated with the initial manifestation of AIDS . </Li>

Which of the following factors are associated with burkitt’s lymphoma formation