<Li> Important in protein degradation . <Ul> <Li> In the late 1990s, it was recognized that phosphorylation of some proteins causes them to be degraded by the ATP - dependent ubiquitin / proteasome pathway . These target proteins become substrates for particular E3 ubiquitin ligases only when they are phosphorylated . </Li> </Ul> </Li> <Ul> <Li> In the late 1990s, it was recognized that phosphorylation of some proteins causes them to be degraded by the ATP - dependent ubiquitin / proteasome pathway . These target proteins become substrates for particular E3 ubiquitin ligases only when they are phosphorylated . </Li> </Ul> <Li> In the late 1990s, it was recognized that phosphorylation of some proteins causes them to be degraded by the ATP - dependent ubiquitin / proteasome pathway . These target proteins become substrates for particular E3 ubiquitin ligases only when they are phosphorylated . </Li> <Li> Important in glycolysis . </Li>

One direct effect of phosphorylating a protein is
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