<P> Hydrophobia is commonly associated with furious rabies, which affects 80% of rabies - infected people . The remaining 20% may experience a paralytic form of rabies that is marked by muscle weakness, loss of sensation, and paralysis; this form of rabies does not usually cause fear of water . </P> <P> Rabies is caused by a number of lyssaviruses including the rabies virus and Australian bat lyssavirus . </P> <P> The rabies virus is the type species of the Lyssavirus genus, in the family Rhabdoviridae, order Mononegavirales . Lyssavirions have helical symmetry, with a length of about 180 nm and a cross-section of about 75 nm . These virions are enveloped and have a single - stranded RNA genome with negative sense . The genetic information is packed as a ribonucleoprotein complex in which RNA is tightly bound by the viral nucleoprotein . The RNA genome of the virus encodes five genes whose order is highly conserved: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and the viral RNA polymerase (L). </P> <P> Once within a muscle or nerve cell, the virus undergoes replication . The trimeric spikes on the exterior of the membrane of the virus interact with a specific cell receptor, the most likely one being the acetylcholine receptor . The cellular membrane pinches in a procession known as pinocytosis and allows entry of the virus into the cell by way of an endosome . The virus then uses the acidic environment, which is necessary, of that endosome and binds to its membrane simultaneously, releasing its five proteins and single strand RNA into the cytoplasm . </P>

When was the last time someone died from rabies