<Table> <Tr> <Th_colspan="4"> CFTR121 </Th> </Tr> <Tr> <Td_colspan="4"> </Td> </Tr> <Tr> <Td_colspan="4"> <Table> <Tr> <Th_colspan="4"> Available structures </Th> </Tr> <Tr> <Th> PDB </Th> <Td_colspan="2"> Ortholog search: PDBe RCSB </Td> </Tr> <Tr> <Td> <Table> <Tr> <Th_colspan="2"> (show) List of PDB id codes </Th> </Tr> <Tr> <Td_colspan="2"> <P> 1XMI, 1XMJ, 2BBO, 2BBS, 2BBT, 2LOB, 2PZE, 2PZF, 2PZG, 3GD7, 3ISW, 4WZ6, 5D2D, 5D3E, 5D3F </P> </Td> </Tr> </Table> </Td> </Tr> </Table> </Td> </Tr> <Tr> <Th_colspan="4"> Identifiers </Th> </Tr> <Tr> <Th> Aliases </Th> <Td_colspan="3"> CFTR, ABC35, ABCC7, CF, CFTR / MRP, MRP7, TNR - dJ760C5. 1, cystic fibrosis transmembrane conductance regulator </Td> </Tr> <Tr> <Th> External IDs </Th> <Td_colspan="3"> OMIM: 602421 MGI: 88388 HomoloGene: 55465 GeneCards: CFTR </Td> </Tr> <Tr> <Th> EC number </Th> <Td_colspan="3"> 3.6. 3.49 </Td> </Tr> <Tr> <Td_colspan="4"> <Table> <Tr> <Th_colspan="4"> (hide) Gene location (Human) </Th> </Tr> <Tr> <Td_colspan="4"> </Td> </Tr> <Tr> <Th> Chr . </Th> <Td_colspan="3"> Chromosome 7 (human) </Td> </Tr> <Tr> <Td_colspan="4"> </Td> </Tr> <Tr> <Th> Band </Th> <Td> 7q31. 2 </Td> <Th> Start </Th> <Td> 117,465,784 bp </Td> </Tr> <Tr> <Th> End </Th> <Td> 117,715,971 bp </Td> </Tr> </Table> </Td> </Tr> <Tr> <Td_colspan="4"> <Table> <Tr> <Th_colspan="4"> (show) Gene location (Mouse) </Th> </Tr> <Tr> <Td_colspan="4"> </Td> </Tr> <Tr> <Th> Chr . </Th> <Td_colspan="3"> Chromosome 6 (mouse) </Td> </Tr> <Tr> <Td_colspan="4"> </Td> </Tr> <Tr> <Th> Band </Th> <Td> 6 A2 6 8.1 cM </Td> <Th> Start </Th> <Td> 18,170,687 bp </Td> </Tr> <Tr> <Th> End </Th> <Td> 18,322,768 bp </Td> </Tr> </Table> </Td> </Tr> <Tr> <Td_colspan="4"> <Table> <Tr> <Th_colspan="4"> (show) Gene ontology </Th> </Tr> <Tr> <Th> Molecular function </Th> <Td> nucleotide binding PDZ domain binding chloride transmembrane transporter activity protein binding chloride channel inhibitor activity enzyme binding hydrolase activity ATP binding chloride channel activity ATPase - coupled anion transmembrane transporter activity chloride channel regulator activity ATPase activity, coupled to transmembrane movement of substances intracellular ATPase - gated chloride channel activity ATPase activity bicarbonate transmembrane transporter activity </Td> </Tr> <Tr> <Th> Cellular component </Th> <Td> cytoplasm recycling endosome endosome early endosome membrane membrane plasma membrane chloride channel complex protein complex cell surface lysosomal membrane early endosome Golgi - associated vesicle membrane endoplasmic reticulum Sec complex extracellular exosome cytosol endosome membrane clathrin - coated vesicle membrane integral component of membrane apical plasma membrane endoplasmic reticulum endoplasmic reticulum membrane recycling endosome membrane integral component of plasma membrane </Td> </Tr> <Tr> <Th> Biological process </Th> <Td> positive regulation of cyclic nucleotide - gated ion channel activity intracellular pH elevation membrane hyperpolarization positive regulation of voltage - gated chloride channel activity cholesterol transport ion transport vesicle docking involved in exocytosis transmembrane transport sperm capacitation positive regulation of insulin secretion involved in cellular response to glucose stimulus cholesterol biosynthetic process positive regulation of exocytosis chloride transport cellular response to cAMP protein deubiquitination membrane organization ATP hydrolysis coupled anion transmembrane transport chloride transmembrane transport transepithelial water transport multicellular organismal water homeostasis cellular response to forskolin bicarbonate transport transport </Td> </Tr> <Tr> <Td_colspan="4"> Sources: Amigo / QuickGO </Td> </Tr> </Table> </Td> </Tr> <Tr> <Th_colspan="4"> Orthologs </Th> </Tr> <Tr> <Th> Species </Th> <Td> Human </Td> <Td> Mouse </Td> </Tr> <Tr> <Th> Entrez </Th> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> 1080 </P> </Td> </Tr> </Table> </Td> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> 12638 </P> </Td> </Tr> </Table> </Td> </Tr> <Tr> <Th> Ensembl </Th> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> ENSG00000001626 </P> </Td> </Tr> </Table> </Td> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> ENSMUSG00000041301 </P> </Td> </Tr> </Table> </Td> </Tr> <Tr> <Th> UniProt </Th> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> P13569 </P> </Td> </Tr> </Table> </Td> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> P26361 </P> </Td> </Tr> </Table> </Td> </Tr> <Tr> <Th> RefSeq (mRNA) </Th> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> NM_000492 </P> </Td> </Tr> </Table> </Td> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> NM_021050 </P> </Td> </Tr> </Table> </Td> </Tr> <Tr> <Th> RefSeq (protein) </Th> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> NP_000483 </P> </Td> </Tr> </Table> </Td> <Td> <Table> <Tr> <Th_colspan="1"> </Th> </Tr> <Tr> <Td_colspan="1"> <P> NP_066388 </P> </Td> </Tr> </Table> </Td> </Tr> <Tr> <Th> Location (UCSC) </Th> <Td> Chr 7: 117.47--117.72 Mb </Td> <Td> Chr 7: 18.17--18.32 Mb </Td> </Tr> <Tr> <Th> PubMed search </Th> <Td> </Td> <Td> </Td> </Tr> <Tr> <Td_colspan="4"> Wikidata </Td> </Tr> <Tr> <Td_colspan="4"> <Table> <Tr> <Td_colspan="2"> View / Edit Human </Td> <Td_colspan="2"> View / Edit Mouse </Td> </Tr> </Table> </Td> </Tr> </Table> <Tr> <Th_colspan="4"> CFTR121 </Th> </Tr> <Tr> <Td_colspan="4"> <Table> <Tr> <Th_colspan="4"> Available structures </Th> </Tr> <Tr> <Th> PDB </Th> <Td_colspan="2"> Ortholog search: PDBe RCSB </Td> </Tr> <Tr> <Td> <Table> <Tr> <Th_colspan="2"> (show) List of PDB id codes </Th> </Tr> <Tr> <Td_colspan="2"> <P> 1XMI, 1XMJ, 2BBO, 2BBS, 2BBT, 2LOB, 2PZE, 2PZF, 2PZG, 3GD7, 3ISW, 4WZ6, 5D2D, 5D3E, 5D3F </P> </Td> </Tr> </Table> </Td> </Tr> </Table> </Td> </Tr> <Table> <Tr> <Th_colspan="4"> Available structures </Th> </Tr> <Tr> <Th> PDB </Th> <Td_colspan="2"> Ortholog search: PDBe RCSB </Td> </Tr> <Tr> <Td> <Table> <Tr> <Th_colspan="2"> (show) List of PDB id codes </Th> </Tr> <Tr> <Td_colspan="2"> <P> 1XMI, 1XMJ, 2BBO, 2BBS, 2BBT, 2LOB, 2PZE, 2PZF, 2PZG, 3GD7, 3ISW, 4WZ6, 5D2D, 5D3E, 5D3F </P> </Td> </Tr> </Table> </Td> </Tr> </Table>

Cftr is a transmembrane regulator protein. its molecules have 1480 amino acids