<Tr> <Th> Type </Th> <Th> Causes </Th> </Tr> <Tr> <Th> Tumors </Th> <Td> Most cases of hypopituitarism are due to pituitary adenomas compressing the normal tissue in the gland, and rarely other brain tumors outside the gland--craniopharyngioma, meningioma, chordoma, ependymoma, glioma or metastasis from cancer elsewhere in the body . </Td> </Tr> <Tr> <Th> Infection, inflammation and infiltration </Th> <Td> The pituitary may also be affected by infections of the brain (brain abscess, meningitis, encephalitis) or of the gland itself, or it may be infiltrated by abnormal cells (neurosarcoidosis, histiocytosis) or excessive iron (hemochromatosis). Empty sella syndrome is unexplained disappearance of pituitary tissue, probably due to outside pressure . Autoimmune or lymphocytic hypophysitis occurs when the immune system directly attacks the pituitary . </Td> </Tr> <Tr> <Th> Vascular </Th> <Td> As a pregnancy comes to term, a pregnant woman's pituitary gland is vulnerable to low blood pressure, such as may result from hemorrhage; pituitary damage due to bleeding after childbirth is called Sheehan's syndrome . Pituitary apoplexy is hemorrhage or infarction (loss of blood supply) of the pituitary . Other forms of stroke are increasingly recognized as a cause for hypopituitarism . </Td> </Tr>

Hypothalamic amenorrhea will result in the increased secretion of thyroid stimulating hormone (tsh)