<P> After Mithridates' death, many Roman physicians claimed to possess and improve the formula . In keeping with most medical practices of his era, Mithridates' anti-poison routines included a religious component, supervised by the Agari; a group of Scythian shamans derived from Indian Aghoris who never left him . </P> <P> It has been suggested that Russian mystic Rasputin's survival of a poisoning attempt was due to mithridatism, but this has not been proven . </P> <P> Indian epics talk about this practice too . It has been said that, during the rule of the king Chandragupta Maurya (320--298 BC), there was a practice of selecting beautiful girls and administering poison in small amounts until they grew up, thus making them insensitive to poison . These maidens were called vishakanyas (visha = poison, kanya = maiden). It was believed that making love with vishakanyas could result in the death of their partners, hence they were employed to kill enemies . </P> <P> The emperor Bindusara was the son of the first Mauryan emperor Chandragupta Maurya and his queen Durdhara . According to the Rajavalikatha, a Jain work, the original name of this emperor was Simhasena . According to a legend mentioned in the Jain texts, Chandragupta's Guru and advisor Chanakya used to feed the emperor with small doses of poison to build his immunity against possible poisoning attempts by the enemies . One day, Chandragupta, not knowing about the poison, shared his food with his pregnant wife, Queen Durdhara, who was 7 days away from delivery . The queen not immune to the poison collapsed and died within a few minutes . Chanakya entered the room the very time she collapsed, and in order to save the child in the womb, he immediately cut open the dead queen's belly and took the baby out, by that time a drop of poison had already reached the baby and touched its head due to which the child got a permanent blueish spot (a "bindu") on his forehead . Thus, the newborn was named "Bindusara". </P>

Can you build up a tolerance to arsenic