<P> The following is a list of the top 15 independent pharmaceutical & biotechnology companies ranked by their revenue generated in the respective financial year, it does not include biotechnology companies that are now owned by, or part of, larger pharmaceutical groups . </P> <P> The change is the companies relative position in this list, compared to their relative position in the prior year; i.e., an increase would be moving closer to rank 1 and vice-versa . Green cells indicate years where revenue increased compared to the previous year, red cells indicate those years where there has been a decrease . </P> <Table> <Tr> <Th> Rank </Th> <Th> Chg </Th> <Th> Company </Th> <Th> 2017 USD billions </Th> <Th> 2016 USD billions </Th> <Th> 2015 USD billions </Th> <Th> 2014 USD billions </Th> <Th> 2013 USD billions </Th> <Th> 2012 USD billions </Th> <Th> 2011 USD billions </Th> </Tr> <Tr> <Td> </Td> <Td> </Td> <Td> Johnson & Johnson NYSE: JNJ </Td> <Td> 17.80 Q1 18.84 Q2 19.70 Q3 56.34 </Td> <Td> 71.89 </Td> <Td> 70.04 </Td> <Td> 74.30 </Td> <Td> 71.31 </Td> <Td> 67.20 </Td> <Td> 65.00 </Td> </Tr> <Tr> <Td> </Td> <Td> </Td> <Td> Roche OTCQX: RHHBY </Td> <Td> 13.02 Q1 14.14 Q2 13.19 Q3 40.35 </Td> <Td> 50.11 </Td> <Td> 47.70 </Td> <Td> 49.86 </Td> <Td> 48.53 </Td> <Td> 47.80 </Td> <Td> 45.21 </Td> </Tr> <Tr> <Td> </Td> <Td> </Td> <Td> Pfizer NYSE: PFE </Td> <Td> 12.80 Q1 12.90 Q2 13.17 Q3 37.87 </Td> <Td> 52.82 </Td> <Td> 48.85 </Td> <Td> 49.61 </Td> <Td> 51.58 </Td> <Td> 58.99 </Td> <Td> 65.26 </Td> </Tr> <Tr> <Td> </Td> <Td> </Td> <Td> Novartis NYSE: NVS </Td> <Td> 11.54 Q1 12.24 Q2 12.41 Q3 36.19 </Td> <Td> 48.52 </Td> <Td> 49.41 </Td> <Td> 58.00 </Td> <Td> 57.36 </Td> <Td> 56.67 </Td> <Td> 58.57 </Td> </Tr> <Tr> <Td> </Td> <Td> </Td> <Td> Sanofi NYSE: SNY </Td> <Td> 9.42 Q1 10.23 Q1 10.55 Q2 30.74 </Td> <Td> 36.57 </Td> <Td> 36.73 </Td> <Td> 43.07 </Td> <Td> 42.08 </Td> <Td> 46.41 </Td> <Td> 44.34 </Td> </Tr> <Tr> <Td> 6 </Td> <Td> </Td> <Td> Bayer FWB: BAYN </Td> <Td> 10.67 Q1 10.24 Q2 9.36 Q3 30.27 </Td> <Td> 25.27 </Td> <Td> 24.09 </Td> <Td> 25.47 </Td> <Td> 24.17 </Td> <Td> 24.30 </Td> <Td> 23.11 </Td> </Tr> <Tr> <Td> 7 </Td> <Td> </Td> <Td> Merck & Co . NYSE: MRK </Td> <Td> 9.40 Q1 9.93 Q2 10.30 Q2 29.63 </Td> <Td> 39.80 </Td> <Td> 39.50 </Td> <Td> 42.24 </Td> <Td> 44.03 </Td> <Td> 47.27 </Td> <Td> 48.05 </Td> </Tr> <Tr> <Td> 8 </Td> <Td> </Td> <Td> GlaxoSmithKline NYSE: GSK </Td> <Td> 9.58 Q1 9.59 Q2 10.41 Q3 29.58 </Td> <Td> 34.79 </Td> <Td> 29.84 </Td> <Td> 37.96 </Td> <Td> 41.61 </Td> <Td> 39.93 </Td> <Td> 41.39 </Td> </Tr> <Tr> <Td> 9 </Td> <Td> </Td> <Td> AbbVie NYSE: ABBV </Td> <Td> 6.50 Q1 6.94 Q2 7.00 Q3 20.44 </Td> <Td> 25.56 </Td> <Td> 22.82 </Td> <Td> 19.96 </Td> <Td> 18.79 </Td> <Td>--</Td> <Td>--</Td> </Tr> <Tr> <Td> 10 </Td> <Td> </Td> <Td> Gilead Sciences NASDAQ: GILD </Td> <Td> 6.38 Q1 7.05 Q2 6.40 Q3 19.83 </Td> <Td> 30.39 </Td> <Td> 32.15 </Td> <Td> 24.47 </Td> <Td> 10.80 </Td> <Td> 9.70 </Td> <Td> 8.39 </Td> </Tr> <Tr> <Td> 11 </Td> <Td> </Td> <Td> Abbott Laboratories NASDAQ: ABT </Td> <Td> 6.34 Q1 6.60 Q2 6.80 Q3 19.74 </Td> <Td> 20.85 </Td> <Td> 20.41 </Td> <Td> 20.25 </Td> <Td> 21.85 </Td> <Td> 39.87 </Td> <Td> 38.85 </Td> </Tr> <Tr> <Td> 12 </Td> <Td> </Td> <Td> Amgen NASDAQ: AMGN </Td> <Td> 5.46 Q1 5.80 Q2 5.77 Q3 17.03 </Td> <Td> 22.99 </Td> <Td> 21.66 </Td> <Td> 20.06 </Td> <Td> 18.68 </Td> <Td> 17.30 </Td> <Td> 15.58 </Td> </Tr> <Tr> <Td> 13 </Td> <Td> </Td> <Td> Teva Pharmaceutical Industries NASDAQ: TEVA </Td> <Td> 5.63 Q1 5.69 Q2 5.61 Q3 16.93 </Td> <Td> 21.90 </Td> <Td> 20.00 </Td> <Td> 20.27 </Td> <Td> 20.31 </Td> <Td> 18.31 </Td> <Td> 16.12 </Td> </Tr> <Tr> <Td> 14 </Td> <Td> </Td> <Td> Eli Lilly & Co NYSE: LLY </Td> <Td> 5.23 Q1 5.82 Q2 5.66 Q3 16.71 </Td> <Td> 21.22 </Td> <Td> 20.00 </Td> <Td> 19.62 </Td> <Td> 23.11 </Td> <Td> 22.60 </Td> <Td> 24.29 </Td> </Tr> <Tr> <Td> 15 </Td> <Td> </Td> <Td> AstraZeneca NASDAQ: AZN </Td> <Td> 5.41 Q1 5.05 Q2 6.23 Q3 16.69 </Td> <Td> 23.00 </Td> <Td> 24.71 </Td> <Td> 26.10 </Td> <Td> 25.71 </Td> <Td> 27.97 </Td> <Td> 33.59 </Td> </Tr> <Tr> <Td> 16 </Td> <Td> </Td> <Td> Bristol - Myers Squibb NASDAQ: BMY </Td> <Td> 4.93 Q1 5.14 Q2 5.25 Q3 15.32 </Td> <Td> 19.43 </Td> <Td> 16.56 </Td> <Td> 15.88 </Td> <Td> 16.39 </Td> <Td> 17.62 </Td> <Td> 21.24 </Td> </Tr> <Tr> <Td> 17 </Td> <Td> </Td> <Td> Novo Nordisk NYSE: NVO </Td> <Td> 4.08 Q1 4.23 Q2 4.79 Q3 13.10 </Td> <Td> 16.61 </Td> <Td> 16.06 </Td> <Td> 15.83 </Td> <Td> 14.88 </Td> <Td> 13.48 </Td> <Td> 11.56 </Td> </Tr> <Tr> <Td> 18 </Td> <Td> </Td> <Td> Merck Group ETR: MRK </Td> <Td> 4.12 Q1 4.45 Q2 4.31 Q3 12.88 </Td> <Td> 15.80 </Td> <Td> 13.95 </Td> <Td> 14.99 </Td> <Td> 14.77 </Td> <Td> 13.02 </Td> <Td> 12.83 </Td> </Tr> <Tr> <Td> 19 </Td> <Td> </Td> <Td> Shire NASDAQ: SHPG </Td> <Td> 3.57 Q1 3.60 Q2 3.50 Q3 10.67 </Td> <Td> 11.40 </Td> <Td> 6.42 </Td> <Td> 6.00 </Td> <Td> 4.76 </Td> <Td> 4.68 </Td> <Td> 3.50 </Td> </Tr> <Tr> <Td> 20 </Td> <Td> </Td> <Td> Biogen NASDAQ: BIIB </Td> <Td> 2.81 Q1 3.08 Q2 3.07 Q3 8.96 </Td> <Td> 11.40 </Td> <Td> 10.80 </Td> <Td> 9.70 </Td> <Td> 6.90 </Td> <Td> 5.50 </Td> <Td> 5.00 </Td> </Tr> <Tr> <Td_colspan="10"> <P> References: </P> </Td> </Tr> </Table> <Tr> <Th> Rank </Th> <Th> Chg </Th> <Th> Company </Th> <Th> 2017 USD billions </Th> <Th> 2016 USD billions </Th> <Th> 2015 USD billions </Th> <Th> 2014 USD billions </Th> <Th> 2013 USD billions </Th> <Th> 2012 USD billions </Th> <Th> 2011 USD billions </Th> </Tr>

What is the biggest pharmaceutical company in america