<Li> The pontomesencephalotegmental complex acts mainly on M1 receptors in the brainstem, deep cerebellar nuclei, pontine nuclei, locus coeruleus, raphe nucleus, lateral reticular nucleus and inferior olive . It also projects to the thalamus, tectum, basal ganglia and basal forebrain . </Li> <Li> Basal nucleus of Meynert acts mainly on M1 receptors in the neocortex . </Li> <Li> Medial septal nucleus acts mainly on M1 receptors in the hippocampus and parts of the cerebral cortex . </Li> <P> In addition, ACh acts as an important internal transmitter in the striatum, which is part of the basal ganglia . It is released by cholinergic interneurons . In humans, non-human primates and rodents, these interneurons respond to salient environmental stimuli with responses that are temporally aligned with the responses of dopaminergic neurons of the substantia nigra . </P>

Where is the acetylcholine produced and to where does it travel