<P> Rosenberg et al. found that APC directs cholinergic synapse assembly between neurons, a finding with implications for autonomic neuropathies, for Alzheimer's disease, for age - related hearing loss, and for some forms of epilepsy and schizophrenia . </P> <P> APC (gene) has been shown to interact with: </P> <Ul> <Li> ARHGEF4, </Li> <Li> AXIN1, </Li> <Li> BUB1, </Li> <Li> CTNNB1, </Li> <Li> CSNK2B, </Li> <Li> CSNK2A1, </Li> <Li> Catenin (cadherin - associated protein), alpha 1, </Li> <Li> DLG3, </Li> <Li> KIFAP3, </Li> <Li> MAPRE2, </Li> <Li> JUP, </Li> <Li> SIAH1, </Li> <Li> TFAP2A, </Li> <Li> TUBA4A and </Li> <Li> XPO1 . </Li> </Ul> <Li> Catenin (cadherin - associated protein), alpha 1, </Li>

What happens if the apc gene is mutated