<P> Natural selection is commonly equated with survival of the fittest, but this expression originated in Herbert Spencer's Principles of Biology in 1864, five years after Charles Darwin published his original works . Survival of the fittest describes the process of natural selection incorrectly, because natural selection is not only about survival and it is not always the fittest that survives . </P> <P> Darwins theory of natural selection laid the groundwork for modern evolutionary theory, and his experiments and observations showed that the organisms in populations varied from each other, that some of these variations were inherited, and that these differences could be acted on by natural selection . However, he could not explain the source of these variations . Like many of his predecessors, Darwin mistakenly thought that heritable traits were a product of use and disuse, and that features acquired during an organism's lifetime could be passed on to its offspring . He looked for examples, such as large ground feeding birds getting stronger legs through exercise, and weaker wings from not flying until, like the ostrich, they could not fly at all . This misunderstanding was called the inheritance of acquired characters and was part of the theory of transmutation of species put forward in 1809 by Jean - Baptiste Lamarck . In the late 19th century this theory became known as Lamarckism . Darwin produced an unsuccessful theory he called pangenesis to try to explain how acquired characteristics could be inherited . In the 1880s August Weismann's experiments indicated that changes from use and disuse could not be inherited, and Lamarckism gradually fell from favor . </P> <P> The missing information needed to help explain how new features could pass from a parent to its offspring was provided by the pioneering genetics work of Gregor Mendel . Mendel's experiments with several generations of pea plants demonstrated that inheritance works by separating and reshuffling hereditary information during the formation of sex cells and recombining that information during fertilisation . This is like mixing different hands of playing cards, with an organism getting a random mix of half of the cards from one parent, and half of the cards from the other . Mendel called the information factors; however, they later became known as genes . Genes are the basic units of heredity in living organisms . They contain the information that directs the physical development and behavior of organisms . </P> <P> Genes are made of DNA . DNA is a long molecule made up of individual molecules called nucleotides . Genetic information is encoded in the sequence of nucleotides, that make up the DNA, just as the sequence of the letters in words carries information on a page . The genes are like short instructions built up of the "letters" of the DNA alphabet . Put together, the entire set of these genes gives enough information to serve as an "instruction manual" of how to build and run an organism . The instructions spelled out by this DNA alphabet can be changed, however, by mutations, and this may alter the instructions carried within the genes . Within the cell, the genes are carried in chromosomes, which are packages for carrying the DNA . It is the reshuffling of the chromosomes that results in unique combinations of genes in offspring . Since genes interact with one another during the development of an organism, novel combinations of genes produced by sexual reproduction can increase the genetic variability of the population even without new mutations . The genetic variability of a population can also increase when members of that population interbreed with individuals from a different population causing gene flow between the populations . This can introduce genes into a population that were not present before . </P>

Organism have a varied body design name the property which gives the basic difference in body design
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