<P> Monomers are subsequently N - glycosylated, arranged into dimers in the endoplasmic reticulum and into multimers in the Golgi apparatus by crosslinking of cysteine residues via disulfide bonds . With respect to the glycosylation, vWF is one of only a few proteins that carry ABO blood group system antigens . </P> <P> Multimers of vWF can be extremely large,> 20,000 kDa, and consist of over 80 subunits of 250 kDa each . Only the large multimers are functional . Some cleavage products that result from vWF production are also secreted but probably serve no function . </P> <P> Von Willebrand factor's primary function is binding to other proteins, in particular factor VIII, and it is important in platelet adhesion to wound sites . It is not an enzyme and, thus, has no catalytic activity . </P> <P> vWF binds to a number of cells and molecules . The most important ones are: </P>

What is the function of von willebrand factor