<P> A Nissl body, also known as Nissl substance and Nissl material, is a large granular body found in neurons . These granules are of rough endoplasmic reticulum (RER) with rosettes of free ribosomes, and are the site of protein synthesis . It was named after Franz Nissl, a German neuropathologist who invented the Nissl staining method . </P> <P> Nissl bodies can be demonstrated by a method of selective staining developed by Nissl (Nissl staining), using an aniline stain to label extranuclear RNA granules . This staining method is useful to localize the cell body, as it can be seen in the soma and dendrites of neurons, though not in the axon or axon hillock . Due to RNA's basophilic ("base - loving") properties it is stained blue by this method . </P> <P> Nissl bodies show changes under various physiological conditions and in pathological conditions they may dissolve and disappear (chromatolysis). </P>

Nissl's granules are present in which part of neuron