<P> Pericardial fluid is the serous fluid secreted by the serous layer of the pericardium into the pericardial cavity . The pericardium consists of two layers, an outer fibrous layer and the inner serous layer . This serous layer has two membranes which enclose the pericardial cavity into which is secreted the pericardial fluid . The fluid is similar to the cerebrospinal fluid of the brain which also serves to cushion and allow some movement of the organ . </P> <P> The pericardial fluid reduces friction within the pericardium by lubricating the epicardial surface allowing the membranes to glide over each other with each heart beat . </P> <P> Ben - Horin et al. (2005) studied the composition of pericardial fluid in patients undergoing open heart surgery . They found that the fluid is made up of a high concentration of lactate dehydrogenase (LDH), protein and lymphocytes . In a healthy adult there is up to 50 ml of clear, straw - coloured fluid . However, there is little data on the normal composition of pericardial fluid to serve as a reference . </P>

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