<P> Selye was of Austro - Hungarian origin, his father was of Hungarian ethnicity while his mother was Austrian . His father a doctor moved back to Budapest with his Austrian wife . Selye's mother died in 1956 from bullet hits during the revolution . He conducted a lecture in 1973 at the Hungarian Scientific Academy in Hungarian with no accent though he had lived many years abroad . </P> <P> His last inspiration for general adaptation syndrome (GAS, a theory of stress) came from an endocrinological experiment in which he injected mice with extracts of various organs . He at first believed he had discovered a new hormone, but was proved wrong when every irritating substance he injected produced the same symptoms (swelling of the adrenal cortex, atrophy of the thymus, gastric and duodenal ulcers). This, paired with his observation that people with different diseases exhibit similar symptoms, led to his description of the effects of "noxious agents" as he at first called it . He later coined the term "stress", which has been accepted into the lexicon of most other languages . </P> <P> Selye has acknowledged the influence of Claude Bernard (who developed the idea of milieu intérieur) and Walter Cannon's "homeostasis". Selye conceptualized the physiology of stress as having two components: a set of responses which he called the "general adaptation syndrome", and the development of a pathological state from ongoing, unrelieved stress . </P> <P> Selye discovered and documented that stress differs from other physical responses in that stress is stressful whether one receives good or bad news, whether the impulse is positive or negative . He called negative stress "distress" and positive stress "eustress". The system whereby the body copes with stress, the hypothalamic - pituitary - adrenal axis (HPA axis) system, was also first described by Selye . He also pointed to an "alarm state", a "resistance state", and an "exhaustion state", largely referring to glandular states . Later he developed the idea of two "reservoirs" of stress resistance, or alternatively stress energy . </P>

Who created the general adaptation syndrome for stress
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