<P> Cancer can develop in any part of the larynx, but the cure rate is affected by the location of the tumour . For the purposes of tumour staging, the larynx is divided into three anatomical regions: the glottis (true vocal cords, anterior and posterior commissures); the supraglottis (epiglottis, arytenoids and aryepiglottic folds, and false cords); and the subglottis . </P> <P> Most laryngeal cancers originate in the glottis . Supraglottic cancers are less common, and subglottic tumours are least frequent . </P> <P> Laryngeal cancer may spread by direct extension to adjacent structures, by metastasis to regional cervical lymph nodes, or more distantly, through the blood stream . Distant metastases to the lung are most common . In 2013 it resulted in 88,000 deaths up from 76,000 deaths in 1990 . Five year survival rates in the United States are 60% . </P> <P> The symptoms of laryngeal cancer depend on the size and location of the tumour . Symptoms may include the following: </P>

Where does cancer of the larynx spread to
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