<P> A number of features of ICP suggest that environmental factors also have a role in the disease: </P> <Ul> <Li> It has been reported that the incidence of ICP is higher in winter than summer . </Li> <Li> The incidence of ICP in Chile has dropped from 14% of pregnancies before 1975 to less than 2% in 1997 . </Li> <Li> ICP recurs in between 45% and 70% of subsequent pregnancies . </Li> <Li> Low serum selenium levels have been linked to ICP, although the role of selenium in bile secretion is not known . </Li> </Ul> <Li> It has been reported that the incidence of ICP is higher in winter than summer . </Li> <Li> The incidence of ICP in Chile has dropped from 14% of pregnancies before 1975 to less than 2% in 1997 . </Li>

What is intrahepatic cholestasis of pregnancy (icp)