<Tr> <Th> Box office </Th> <Td> $312.2 million </Td> </Tr> <P> Resident Evil: The Final Chapter is a 2016 science fiction action horror film written and directed by Paul W.S. Anderson . It is the sequel to Resident Evil: Retribution (2012) and the sixth and final installment in the Resident Evil film series, which is loosely based on the Capcom survival horror video game series Resident Evil . The film stars Milla Jovovich, Ali Larter, Shawn Roberts, Ruby Rose, Eoin Macken, William Levy, and Iain Glen . In the film, Alice and her friends are betrayed by Albert Wesker, who gathers the entire forces of Umbrella into one final strike against the apocalypse survivors . </P> <P> Resident Evil: The Final Chapter was released on December 23, 2016, in Japan and on January 27, 2017, in the United States in 2D, 3D and IMAX 3D . The film received mixed reviews and became the highest - grossing film in the franchise, earning over $312 million worldwide . </P> <P> Dr. James Marcus, the original founder of the Umbrella Corporation, had a daughter who was dying of premature aging . Desperate to save her, Marcus discovered the T - virus . Unfortunately, the virus had the side effect of sudden and uncontrollable mutation; in Cape Town, South Africa, a boy dies in a cable car ascending to Table Mountain, then suddenly reanimates and kills the other passengers . Marcus tried to have the program shut down, despite protests from his colleague Dr. Alexander Isaacs to continue to use it . When he refused, Isaacs ordered Albert Wesker to kill Marcus . The Red Queen is then created using the images of Marcus's daughter from her childhood . </P>

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