<P> It sources its versatile capacity for degradation by import of enzymes with specificity for different substrates; cathepsins are the major class of hydrolytic enzymes, while lysosomal alpha - glucosidase (GAA) is responsible for carbohydrates, and ACP is necessary to release phosphate groups of phospholipids . </P> <P> Many components of animal cells are recycled by transferring them inside or embedded in sections of membrane . For instance, in endocytosis (more specifically, macropinocytosis), a portion of the cell's plasma membrane pinches off to form a vesicle that will eventually fuse with an organelle within the cell . Without active replenishment, the plasma membrane would continuously decrease in size . It is thought that lysosomes participate in this dynamic membrane exchange system and are formed by a gradual maturation process from endosomes . </P> <P> The production of lysosomal proteins suggests one method of lysosome sustainment . Lysosomal protein genes are transcribed in the nucleus . mRNA transcripts exit the nucleus into the cytosol, where they are translated by ribosomes . The nascent peptide chains are translocated into the rough endoplasmic reticulum, where they are modified . Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport, a specific lysosomal tag, mannose 6 - phosphate, is added to the peptides . The presence of these tags allow for binding to mannose 6 - phosphate receptors in the Golgi apparatus, a phenomenon that is crucial for proper packaging into vesicles destined for the lysosomal system . </P> <P> Upon leaving the Golgi apparatus, the lysosomal enzyme - filled vesicle fuses with a late endosome, a relatively acidic organelle with an approximate pH of 5.5 . This acidic environment causes dissociation of the lysosomal enzymes from the mannose 6 - phosphate receptors . The enzymes are packed into vesicles for further transport to established lysosomes . The late endosome itself can eventually grow into a mature lysosome, as evidenced by the transport of endosomal membrane components from the lysosomes back to the endosomes . </P>

Which organelle makes the digestive enzymes of lysosome