<Li> Conservative replication would leave the two original template DNA strands together in a double helix and would produce a copy composed of two new strands containing all of the new DNA base pairs . </Li> <Li> Dispersive replication would produce two copies of the DNA, both containing distinct regions of DNA composed of either both original strands or both new strands . </Li> <P> The deciphering of the structure of DNA by Watson and Crick in 1953 suggested that each strand of the double helix would serve as a template for synthesis of a new strand . However, there was no way of knowing how the newly synthesized strands might combine with the template strands to form two double helical DNA molecules . The semiconservative model seemed most reasonable since it would allow each daughter strand to remain associated with its template strand . The semiconservative model was anticipated by Nikolai Koltsov, supported by the Meselson - Stahl experiment and other even more revealing experiments that allowed for autoradiographic visualization of the distribution of old and new strands within replicated chromosomes . </P> <P> Experimental evidence confirmed that two lines were observed, therefore offering compelling evidence for the semi-conservative theory . </P>

Who proposed the semiconservative model of dna replication
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