<Li> Iain Glen as Dr. Alexander Isaacs (and one clone), the technologically enhanced CEO of the Umbrella Corporation previously thought to have been killed by Alice (it was a clone). He maniacally intended to use the T - Virus to start a biblical apocalypse, wiping out most of humanity and leaving a few tens of thousands alive, so as to remake the world with Umbrella's designs . He is eventually killed by an Issacs clone that Alice had earlier encountered en route to the city; the clone is shortly killed afterwards by the undead . </Li> <Li> Ali Larter as Claire Redfield, one of Alice's closest allies, formerly led the convoy of survivors in the Nevada desert, and had gone missing along with her brother, Chris Redfield, after Umbrella's assault on Arcadia . She joins Alice and the others on the mission to the Hive to defeat Isaacs . </Li> <Li> Shawn Roberts as Albert Wesker, the former chairman of Umbrella who is the personal subordinate of Dr. Isaacs, and is also the mastermind of the plot which has betrayed Alice once again after the events of the previous film . After the Red Queen slammed a door that amputated his legs, Alice gives him the deadman's trigger to bombs she has planted inside the Hive - allowing her and Claire to escape as she slowly passes out from blood loss . He eventually dies and is consequently blown up in the explosion along with all the remaining members of Umbrella - including Alicia . </Li> <Li> Eoin Macken as Doc, a spy working for Umbrella, posing as one of the survivors as assigned by Isaacs to find Alice . He is later killed by Claire Redfield for his treachery . </Li>

Who plays wesker in resident evil final chapter