<P> Z Nation is an American action / horror / comedy - drama / post-apocalyptic television series that airs on Syfy, created by Karl Schaefer and Craig Engler, and produced by The Asylum . The first season of 13 episodes premiered on September 12, 2014 . Z Nation is filmed in the Spokane, Washington, area . </P> <P> On June 16, 2016, Syfy announced that Z Nation's third season would be preceded by a TV movie, set prior to the climax of season 2 and introducing central characters for the third season . However, the movie was instead presented as the first two episodes of the season, the two - part "No Mercy". </P> <P> On November 29, 2016, Syfy renewed the series for a 13 - episode fourth season, which premiered on September 29, 2017 . </P> <P> Z Nation begins three years into a virus - caused zombie apocalypse, which has already killed most humans . In the days just before society fell apart, Murphy was one of three inmates at Portsmouth Naval Prison in Kittery, Maine, who were unwilling participants in a government - approved experiment . Each inmate was given a different test vaccine . Murphy was the only one to survive the vaccine injection . He is the only known survivor of a zombie bite who did not himself turn into a zombie, and his blood contains antibodies that are mankind's last and best hope for a vaccine . </P>

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