<Tr> <Th> MeSH </Th> <Td> D007801 </Td> </Tr> <Tr> <Td_colspan="2"> Anatomical terms of microanatomy (edit on Wikidata) </Td> </Tr> <P> Langerhans cells are dendritic cells (antigen - presenting immune cells) of the skin, and contain organelles called Birbeck granules . They are present in all layers of the epidermis and are most prominent in the stratum spinosum . They also occur in the papillary dermis, particularly around blood vessels, as well as in the mucosa of the mouth, foreskin, and vaginal epithelium . They can be found in other tissues, such as lymph nodes, particularly in association with the condition Langerhans cell histiocytosis (LCH). </P> <P> In skin infections, the local Langerhans cells take up and process microbial antigens to become fully functional antigen - presenting cells . </P>

Where are dendritic cells located in the epidermis
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