<P> Dapoxetine is a white powder substance and water - insoluble . Taken 1--3 hours before sexual activity, it is rapidly absorbed in the body . Its maximum plasma concentration (C) is reached 1--2 hours after oral administration . The C and AUC (Area Under the plasma vs. time Curve) are dose dependent . The C and Tm (time needed to obtain the maximum plasma concentration) after single doses of dapoxetine 30 mg and 60 mg are 297 and 498 ng / mL at 1.01 and 1.27 hours respectively . A high fat meal does reduce the C slightly, but it is insignificant . In fact, food doesn't alter dapoxetine pharmacokinetics . Dapoxetine can be taken with or without food . </P> <Dl> <Dt> Distribution </Dt> </Dl> <P> Dapoxetine is absorbed and distributed rapidly in the body . Greater than 99% of dapoxetine is bound to the plasma protein . The mean steady state volume is 162 L. Its initial half - life is 1.31 hours (30 mg dose) and 1.42 hours (60 mg dose,) and its terminal half life is 18.7 hours (30 mg dose) and 21.9 hours (60 mg dose). </P> <Dl> <Dt> Metabolism </Dt> </Dl>

How long does dapoxetine stay in your system
find me the text answering this question