<Table> <Tr> <Td> ← SR 39 </Td> <Td> </Td> <Td> SR 40 → </Td> </Tr> </Table> <Tr> <Td> ← SR 39 </Td> <Td> </Td> <Td> SR 40 → </Td> </Tr> <P> Interstate 40 (I - 40) traverses the entirety of the state of Tennessee from west to east, running from the Mississippi River at the Arkansas border to the northern base of the Great Smoky Mountains at the North Carolina border . The road connects Tennessee's three largest cities--Memphis, Nashville, and Knoxville--and crosses all of Tennessee's physiographical provinces and Grand Divisions--the Mississippi Embayment and Gulf Coastal Plain in West Tennessee, the Highland Rim and Nashville Basin in Middle Tennessee, and the Cumberland Plateau, Appalachian Valley and Ridge Province, and Blue Ridge Province in East Tennessee . The Tennessee section of I - 40 is 452 miles (727 km) long, the longest of any state . </P> <P> I - 40 enters Tennessee from Arkansas via the six lane Hernando de Soto Bridge, which spans the Mississippi River at river mile 736 . Immediately within the city of Memphis, the interstate passes across the southern half of Mud Island before crossing the Wolf River Harbor into downtown Memphis . Throughout Memphis, the highway contains a minimum of six through lanes, except through major interchanges . About one mile from the state line is an interchange with the western terminus of Interstate 240, where I - 40 abruptly turns north, following a route formerly designated as part of I - 240 . About one mile later, the highway has an interchange with State Route 300, a connector to US 51 and the future Interstate 69 . At this interchange, the interstate turns east and enters a stretch designated as the Dr. Martin Luther King Jr . Memorial Expressway . I - 40 crosses the Wolf River three times in Memphis as the road passes near the neighborhoods of Frayser and Raleigh and turns southeast . A few miles later, I - 40 has an interchange with I - 240 southbound and Sam Cooper Boulevard eastbound, and turns sharp northeast, leaving Memphis . For the next several miles the highway is known as the Isaac Hayes Memorial Highway and is eight lanes, the left lanes functioning as HOV lanes during rush hour, passing through several major suburbs of Memphis, including Bartlett, Cordova, and Lakeland . At exit 18, which is with US 64, the highway narrows to six lanes, and to four lanes a short distance beyond . Several miles later, near Arlington, is a cloverleaf interchange with I - 269 . </P>

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