<P> Season two increased in ratings, averaging 4.50 million viewers weekly, and is currently the highest season . </P> <P> Warner Home Video released the complete second season, under the title of One Tree Hill: The Complete Second Season, on September 13, 2005, as a six - disc boxed set . </P> <P> Season 2 chronicles the remainder of junior year at Tree Hill High . Lucas and Nathan begin to bond as brothers . Peyton experiments with drugs . Both Karen and Keith find new loves, but Keith doesn't find happiness when he finds out Dan hired her to break his heart . Haley leaves town to go on tour, breaking Nathan's heart . Brooke goes on a journey of self - discovery while Peyton falls in love and gets involved with drugs when she has to leave . </P> <Table> <Tr> <Td> <H3> Regular (edit) </H3> <Ul> <Li> Chad Michael Murray as Lucas Scott (23 episodes) </Li> <Li> James Lafferty as Nathan Scott (23 episodes) </Li> <Li> Hilarie Burton as Peyton Sawyer (22 episodes) </Li> <Li> Bethany Joy Lenz as Haley James Scott (20 episodes) </Li> <Li> Paul Johansson as Dan Scott (20 episodes) </Li> <Li> Sophia Bush as Brooke Davis (23 episodes) </Li> <Li> Barbara Alyn Woods as Deb Scott (17 episodes) </Li> <Li> Barry Corbin as Whitey Durham (12 episodes) </Li> <Li> Craig Sheffer as Keith Scott (16 episodes) </Li> <Li> Moira Kelly as Karen Roe (23 episodes) </Li> </Ul> </Td> <Td> <H3> Recurring (edit) </H3> <Ul> <Li> Kieren Hutchison as Andy Hargrove (17 episodes) </Li> <Li> Lee Norris as Mouth McFadden (15 episodes) </Li> <Li> Daniella Alonso as Anna Taggaro (12 episodes) </Li> <Li> Michael Copon as Felix Taggaro (12 episodes) </Li> <Li> Bryan Greenberg as Jake Jagielski (10 episodes) </Li> <Li> Maria Menounos as Emily Chambers (Jules) (11 episodes) </Li> <Li> Tyler Hilton as Chris Keller (18 episodes) </Li> <Li> Brett Claywell as Tim Smith (8 episodes) </Li> <Li> Vaughn Wilson as Fergie Thompson (7 episodes) </Li> <Li> Katherine Bailess as Erica Marsh (6 episodes) </Li> <Li> Antwon Tanner as Skills Taylor (5 episodes) </Li> <Li> Cullen Moss as Junk Moretti (5 episodes) </Li> <Li> Bevin Prince as Bevin Mirskey (5 episodes) </Li> <Li> Lindsey McKeon as Taylor James (5 episodes) </Li> </Ul> </Td> <Td> <H3> Guest Cast (edit) </H3> <Ul> <Li> Emmanuelle Vaugier as Nicki (4 episodes) </Li> <Li> Shawn Shepard as Principal Turner (3 episodes) </Li> <Li> Bess Armstrong as Lydia James (2 episodes) </Li> <Li> Sarah Edwards as Theresa (2 episodes) </Li> <Li> Michael Trucco as Cooper Lee (1 episode) </Li> </Ul> </Td> </Tr> </Table>

When does haley leave nathan to go on tour