<P> An enzyme that plays an important role in the repair of oxidative DNA damage is the 3' - phosphodiesterase . </P> <P> During the replication of DNA, there is a hole between the phosphates in the backbone left by DNA polymerase I. DNA ligase is able to form a phosphodiester bond between the nucleotides . </P>

Where do covalent bonds form between two deoxyribose nucleotides