<Tr> <Td_colspan="2"> Micrograph of non-alcoholic fatty liver disease, demonstrating marked steatosis (fatty liver appears white). Trichrome stain </Td> </Tr> <Tr> <Th> Specialty </Th> <Td> Gastroenterology </Td> </Tr> <P> Non-alcoholic fatty liver disease (NAFLD) is one of the types of fatty liver which occurs when fat is deposited (steatosis) in the liver due to causes other than excessive alcohol use . Non-alcoholic steatohepatitis (NASH) is the most extreme form of NAFLD . NAFLD is the most common liver disorder in developed countries . </P> <P> NAFLD is related to insulin resistance and the metabolic syndrome and may respond to treatments originally developed for other insulin - resistant states (e.g. diabetes mellitus type 2) such as weight loss, metformin, and thiazolidinediones . Up to 80% of obese people have the disease . NASH is regarded as a major cause of cirrhosis of the liver of unknown cause . Most people have a good outcome if the condition is caught in its early stages . </P>

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