<P> Patients taking carisoprodol for a prolonged time have reported dependence, withdrawal and abuse, although most of these cases were reported by patients who had had a history of addiction . These effects were also reported by patients who took it in combination with other drugs with abuse potential, and in fewer cases, there were reports of carisoprodol - associated abuse when used without other drugs with abuse potential . </P> <P> Common side effects eventually caused by metaxalone include dizziness, headache, drowsiness, nausea, irritability, nervousness, upset stomach and vomiting . Severe side effects may be experienced when consuming metaxalone, such as severe allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue), chills, fever, and sore throat, may require medical attention . Other severe side effects include unusual or severe tiredness or weakness, as well as yellowing of the skin or the eyes . When baclofen is administered intrathecally, it may cause CNS depression accompanied with cardiovascular collapse and respiratory failure . Tizanidine may lower blood pressure . This effect can be controlled by administering a low dose at the beginning and increasing it gradually . </P>

Are relaxation of a muscle and inhibition of a muscle the same thing