<Tr> <Th_colspan="2"> External links </Th> </Tr> <Tr> <Th> Official website </Th> <Td> abc.go.com/shows/greys-anatomy </Td> </Tr> <P> Grey's Anatomy is an American medical drama television series that premiered on March 27, 2005, on American Broadcasting Company (ABC) as a mid-season replacement . The fictional series focuses on the lives of surgical interns, residents, and attending physicians, as they develop into seasoned doctors while trying to maintain personal lives and relationships . The title is a play on Gray's Anatomy, a classic human anatomy textbook first published in 1858 in London and written by Henry Gray . </P> <P> Shonda Rhimes developed the pilot and continues to write for the series; she is also one of the executive producers, along with Betsy Beers, Mark Gordon, Krista Vernoff, Rob Corn, Mark Wilding, and Allan Heinberg . Although the series is set in Seattle (at the fictional Seattle Grace, later known as the Grey - Sloan Memorial Hospital), it is filmed primarily in Los Angeles, California . The show was originally titled Complications, a double - edged reference to both the complicated medical procedures and personal lives of the characters . </P>

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