<Table> <Tr> <Th_colspan="2"> Dr. Izzie Stevens </Th> </Tr> <Tr> <Td_colspan="2"> Grey's Anatomy character </Td> </Tr> <Tr> <Td_colspan="2"> The Season 6 Promotional Photo of Katherine Heigl as Dr. Izzie Stevens </Td> </Tr> <Tr> <Th> First appearance </Th> <Td> "A Hard Day's Night" (1.01) March 27, 2005 </Td> </Tr> <Tr> <Th> Last appearance </Th> <Td> "I Like You So Much Better When You're Naked" (6.12) January 21, 2010 </Td> </Tr> <Tr> <Th> Created by </Th> <Td> Shonda Rhimes </Td> </Tr> <Tr> <Th> Portrayed by </Th> <Td> Katherine Heigl </Td> </Tr> <Tr> <Th_colspan="2"> Information </Th> </Tr> <Tr> <Th> Full name </Th> <Td> Isobel Katherine Stevens </Td> </Tr> <Tr> <Th> Title </Th> <Td> M.D. </Td> </Tr> <Tr> <Th> Family </Th> <Td> Robbie Stevens (Mother) Hannah Klein (Daughter) </Td> </Tr> <Tr> <Th> Spouse (s) </Th> <Td> Alex Karev (divorced) </Td> </Tr> <Tr> <Th> Significant other (s) </Th> <Td> Hank Denny Duquette (fiancé, deceased) George O'Malley (deceased) </Td> </Tr> <Tr> <Th> Religion </Th> <Td> Catholicism </Td> </Tr> </Table> <Tr> <Th_colspan="2"> Dr. Izzie Stevens </Th> </Tr>

Grey's anatomy when do izzie and alex get together