<P> A mysterious recruiter approaches Wilson, offering an experimental cure for his cancer . He is taken to Ajax and Angel Dust, who inject him with a serum designed to awaken latent mutant genes . They then subject him to days of torture to induce stress and trigger any mutation Wade may have, but without success . When Wilson discovers Ajax's real name, Francis, and mocks him for it, Ajax leaves Wilson in a hyperbaric chamber that takes him to the verge of asphyxiation periodically over a weekend . It finally activates a superhuman healing ability that cures his cancer, but leaves him severely disfigured with burn - like scars over his entire body . He escapes from the chamber and attacks Ajax, but relents when told that his disfigurement can be cured . Ajax subdues Wilson and leaves him for dead in the burning laboratory . </P> <P> Wilson survives and seeks out Vanessa, but does not reveal he is alive because he is afraid of how she would react to his new appearance . After consulting his best friend Weasel, Wilson decides to hunt down Ajax for the cure . He becomes a masked vigilante, adopting the name "Deadpool" (from Weasel picking him in a dead pool), and moves into the home of an elderly blind woman named Al . Deadpool questions and murders many of Ajax's men until one, the recruiter, reveals Ajax's whereabouts . Deadpool intercepts Ajax and a convoy of armed men on an expressway, killing everyone but Ajax . He demands the cure, but is interrupted by the X-Man Colossus and his trainee Negasonic Teenage Warhead . Colossus wants Deadpool to mend his ways and join the X-Men . Taking advantage of the distraction, Ajax escapes . He goes to Weasel's bar and learns of Vanessa . </P> <P> Ajax kidnaps Vanessa and takes her to a decommissioned helicarrier in a scrapyard . Deadpool convinces Colossus and Negasonic to help him, and they battle Angel Dust and several soldiers while Deadpool fights his way to Ajax . During the battle, Negasonic accidentally destroys the equipment stabilizing the helicarrier . Deadpool protects Vanessa from the falling ship, while Colossus carries Negasonic and Angel Dust to safety . Ajax attacks Deadpool again but is overpowered . He reveals that there is no cure, and despite Colossus's pleading, Deadpool kills Ajax . Deadpool promises to try and be more heroic moving forward . Though Vanessa is angry at Wilson for leaving her, she reconciles with him . </P> <Ul> <Li> Ryan Reynolds as Wade Wilson / Deadpool: A wisecracking mercenary with accelerated healing but severe scarring over his body after undergoing an experimental mutation . The writers described Deadpool as "fun to hang out with...in short doses", while Reynolds promised a more "authentic" and comic - faithful version of the character than the one he portrayed in X-Men Origins: Wolverine . The character is aware that he is in a film after becoming Deadpool, though before that point Wilson does make a joke about Reynolds's role in Green Lantern . </Li> <Li> Morena Baccarin as Vanessa: An escort and Wilson's fiancée . Baccarin described her as "scrappy" and not a damsel in distress . The character was initially designed as a "typical prostitute", but Baccarin worked with the costume and makeup teams to make her appearance more layered . The film does not explore the character's comic alter - ego "Copycat" as the writers wanted to focus on Deadpool, but makeup designer Bill Corso included some references to Copycat's blue comic appearance . </Li> <Li> Ed Skrein as Francis Freeman / Ajax: An artificially - mutated member of the program that creates Deadpool, he feels no pain and has enhanced strength . Director Tim Miller praised Skrein's dedication to the role, saying "he worked really, really hard" for the fight sequences and completed around 80 percent of his own stunts in the film . Skrein was influenced by Rutger Hauer's Roy Batty from Blade Runner, and serial killer Harold Shipman . </Li> <Li> T.J. Miller as Weasel: Wilson's best friend . Miller felt he was cast as the character because he "looks like his superhero power is spilling mustard on his shirt", and producer Simon Kinberg added that an actor was needed "who could keep up with" Reynolds comedically . Miller attempted to give the character a facial tic, but director Tim Miller rejected the idea . </Li> <Li> Gina Carano as Angel Dust: An artificially - mutated member of the program that creates Deadpool, she has superhuman strength and speed . Director Miller personally called Carano and asked her to take the part . Carano felt the character's rage and "extreme adrenaline issues" made comparisons to the drug "angel dust" fitting . Carano had wanted to wear yellow contact lenses to match the character's look from the comics, but Corso turned her down, comparing them to something from the Twilight films . </Li> <Li> Brianna Hildebrand as Negasonic Teenage Warhead: A teenage X-Men trainee, who possesses the mutant power to detonate atomic bursts from her body . The filmmakers wanted to use the character based on her name, and looked to change her comic abilities from telepathic and precognitive powers to "a literal warhead". They required permission from Marvel to do this, with Tim Miller talking directly with Marvel Studios president Kevin Feige . A deal was reached allowing the change in exchange for 20th Century Fox giving Marvel Studios the film rights for Ego the Living Planet, whom they wanted to use in the 2017 film Guardians of the Galaxy Vol. 2 . </Li> </Ul>

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