<Tr> <Th> Frequency </Th> <Td> 60--95% (adults) </Td> </Tr> <Tr> <Td_colspan="2"> (edit on Wikidata) </Td> </Tr> <P> Herpes simplex is a viral disease caused by the herpes simplex virus . Infections are categorized based on the part of the body infected . Oral herpes involves the face or mouth . It may result in small blisters in groups often called cold sores or fever blisters or may just cause a sore throat . Genital herpes, often simply known as herpes, may have minimal symptoms or form blisters that break open and result in small ulcers . These typically heal over two to four weeks . Tingling or shooting pains may occur before the blisters appear . Herpes cycles between periods of active disease followed by periods without symptoms . The first episode is often more severe and may be associated with fever, muscle pains, swollen lymph nodes and headaches . Over time, episodes of active disease decrease in frequency and severity . Other disorders caused by herpes simplex include: herpetic whitlow when it involves the fingers, herpes of the eye, herpes infection of the brain, and neonatal herpes when it affects a newborn, among others . </P> <P> There are two types of herpes simplex virus, type 1 (HSV - 1) and type 2 (HSV - 2). HSV - 1 more commonly causes infections around the mouth while HSV - 2 more commonly causes genital infections . They are transmitted by direct contact with body fluids or lesions of an infected individual . Transmission may still occur when symptoms are not present . Genital herpes is classified as a sexually transmitted infection . It may be spread to an infant during childbirth . After infection, the viruses are transported along sensory nerves to the nerve cell bodies, where they reside lifelong . Causes of recurrence may include: decreased immune function, stress, and sunlight exposure . Oral and genital herpes is usually diagnosed based on the presenting symptoms . The diagnosis may be confirmed by viral culture or detecting herpes DNA in fluid from blisters . Testing the blood for antibodies against the virus can confirm a previous infection but will be negative in new infections . </P>

Herpes simplex virus is a common cause of
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