<Ul> <Li> Schizophrenia </Li> <Li> Schizoaffective disorder most commonly in conjunction with either an antidepressant (in the case of the depressive subtype) or a mood stabiliser (in the case of the bipolar subtype). </Li> <Li> Bipolar disorder (acute mania and mixed episodes) may be treated with either typical or atypical antipsychotics, although atypical antipsychotics are usually preferred because they tend to have more favourable adverse effect profiles and, according to a recent meta - analysis, they tend to have a lower liability for causing conversion from mania to depression . </Li> <Li> Psychotic depression . In this indication it is a common practice for the psychiatrist to prescribe a combination of an atypical antipsychotic and an antidepressant as this practice is best supported by the evidence . </Li> <Li> Treatment - resistant (and not necessarily psychotic) major depression as an adjunct to standard antidepressant therapy . </Li> </Ul> <Li> Schizoaffective disorder most commonly in conjunction with either an antidepressant (in the case of the depressive subtype) or a mood stabiliser (in the case of the bipolar subtype). </Li> <Li> Bipolar disorder (acute mania and mixed episodes) may be treated with either typical or atypical antipsychotics, although atypical antipsychotics are usually preferred because they tend to have more favourable adverse effect profiles and, according to a recent meta - analysis, they tend to have a lower liability for causing conversion from mania to depression . </Li> <Li> Psychotic depression . In this indication it is a common practice for the psychiatrist to prescribe a combination of an atypical antipsychotic and an antidepressant as this practice is best supported by the evidence . </Li>

What is the mechanism of action of antipsychotic drugs