<P> Preacher is an American television series developed by Sam Catlin, Evan Goldberg, and Seth Rogen for AMC starring Dominic Cooper . It is an adaptation of the comic book series Preacher created by Garth Ennis and Steve Dillon, and published by DC Comics' Vertigo imprint . The series was officially picked up on September 9, 2015, with a ten - episode order which premiered on May 22, 2016 . On June 29, 2016, AMC renewed the series for a 13 - episode second season that premiered on June 25, 2017 . </P> <Ul> <Li> Dominic Cooper as Jesse Custer, a small - town preacher with a criminal past and a newly discovered superpower to command others to do as he says . Dominic Ruggieri portrays 10 - year - old Jesse . </Li> <Li> Joseph Gilgun as Cassidy, a vice-loving vampire who's proud to join Jesse on his search for God . </Li> <Li> Ruth Negga as Tulip O'Hare, Jesse's volatile, hell - raising girlfriend . Ashley Aufderheide portrays 10 - year old Tulip . </Li> <Li> Lucy Griffiths as Emily Woodrow, a single mother, waitress, church organist, bookkeeper, and Jesse's loyal right hand . (season 1) </Li> <Li> W. Earl Brown as Sheriff Hugo Root, Annville's local lawman . (main season 1; guest season 2) </Li> <Li> Derek Wilson as Donnie Schenck, Odin Quincannon's right - hand man . (season 1) </Li> <Li> Ian Colletti as Eugene "Arseface" Root, Jesse's most faithful parishioner, and Sheriff Root's son . </Li> <Li> Tom Brooke as Fiore, one of two Adephi angels tasked with watching the half - demon, half - angelic creature named Genesis . (main season 1; guest season 2) </Li> <Li> Anatol Yusef as DeBlanc, one of two Adephi angels tasked with watching the half - demon, half - angelic creature named Genesis . (season 1) </Li> <Li> Graham McTavish as The Saint of Killers, a supernatural, unstoppable killing machine summoned from Hell to destroy Jesse . </Li> <Li> Pip Torrens as Herr Starr, member of the Grail, a powerful, super-secret organization . Starr was briefly introduced in the season 1 episode "The Possibilities", although played by a different actor . (cameo season 1; main season 2) </Li> <Li> Noah Taylor as Adolf Hitler (season 2) </Li> <Li> Julie Ann Emery as Lara Featherstone, one of the Grail's best operatives . (season 2) </Li> </Ul> <Li> Dominic Cooper as Jesse Custer, a small - town preacher with a criminal past and a newly discovered superpower to command others to do as he says . Dominic Ruggieri portrays 10 - year - old Jesse . </Li> <Li> Joseph Gilgun as Cassidy, a vice-loving vampire who's proud to join Jesse on his search for God . </Li>

What is the premise of the show preacher