<Li> Outside the body hemoglobin saturates completely with oxygen in the ambient environment to HbO . Due to a decreasing availability of cytochrome b5, necessary for reduction of met - Hb, the transition of HbO into met - Hb will, in contrast to inside the body, no longer be reversed . Once hemoglobin is autooxidized to met - Hb it will denature to hemichrome (HC), which is formed by an internal conformation change to the heme group . </Li> <P> In physics there are two continuous physical states of matter, solid and fluid . Once blood has left the body it behaves as a fluid and all physical laws apply . </P> <Ul> <Li> Gravity acts on blood (without the body's influence) as soon as it exits the body . Given the right circumstances blood can act according to ballistic theory . </Li> <Li> Viscosity is the amount of internal friction in the fluid . It describes the resistance of a liquid to flow . </Li> <Li> Surface tension is the force that maintains the shape of a drop of liquid, such as blood . When two fluids are in contact with each other (blood and air) there are forces attracting all molecules to each other . </Li> </Ul> <Li> Gravity acts on blood (without the body's influence) as soon as it exits the body . Given the right circumstances blood can act according to ballistic theory . </Li>

Where were the first studies of blood spatter analysis conducted