<Li> Tim Allen as Mike Baxter: Mike is a father of three daughters and the director of marketing for the Outdoor Man chain of sporting goods stores . He fervently supports "traditional" American values, is a Protestant and is politically conservative . Mike loves his daughters but says his favorite is Eve, the youngest and most athletic daughter, and whose political opinions and interests mirror his own . He is proud of her ability to excel at anything she tries, including school work, hunting and playing sports . Mike often finds himself annoyed with Outdoor Man's young slow - witted employee Kyle (who later becomes his son - in - law), and with Ryan, his politically liberal son - in - law married to his oldest daughter, and the father of Mike's grandson, Boyd . The video blog or "vlog" that Mike does for Outdoor Man is frequently used as a vehicle to rant about his political views . Mike is a graduate of the University of Michigan, and an amateur radio operator using the call sign KA0XTT . </Li> <Li> Nancy Travis as Vanessa Baxter, Mike's wife: Vanessa is a geologist working in the energy industry for a company that does hydraulic fracturing, or "fracking". In season four, Vanessa becomes frustrated with her job and decides to go back to college to become a high school science teacher . After being fired as a teacher due to budget cuts, Vanessa begins her own tutoring business . Vanessa was ambiguous in her political views until season five, when she announces she is supporting Hillary Clinton for president, mainly because she thinks it will advance women's causes . She is shown drinking wine frequently, and is also frequently mocked by Mike and her daughters about it . She is a graduate of Ohio State University with a Master of Science degree in Physics and a PhD in Geology . Vanessa often makes attempts to be politically correct, but only highlights how uncomfortable she is trying to relate to people of other races . Despite this, she and her African - American neighbor Carol Larabee seem to get along . Vanessa's humor includes bad puns, which irritate Mike and the girls no end . </Li> <Li> Amanda Fuller (seasons 2--present) and Alexandra Krosney (season 1) as Kristin Beth Baxter, the oldest daughter: Kristin, unlike her father, espouses liberal political views and her views with regard to Christianity seem ambiguous . During her senior year of high school, Kristin became pregnant with her son, Boyd . She was a single mother living in the Baxter home until moving out in the season two finale . She began to reconcile with Boyd's father, Ryan Vogelson, in season three, and the two get married between seasons four and five . Kristin worked at a diner until landing a job at an upscale restaurant run by a former co-worker at the end of season two . In season four, she becomes the manager of the new restaurant opened by Outdoor Man . Kristin tends to work extra hard in this new job to prove she did not get the position through nepotism, despite Mike and Ed frequently telling her she was qualified . Alexandra Krosney portrayed Kristin in the show's first season (despite being nearly two years younger than Molly Ephraim, playing Kristin's younger sister); Krosney was replaced by Amanda Fuller prior to season two for unspecified creative reasons . </Li> <Li> Molly Ephraim (seasons 1--6) and Molly McCook (recurring, season 7) as Amanda Elaine "Mandy" Baxter - Anderson, the middle daughter: Mandy is not as academic as her sisters (and she has a penchant for cutting class and ignoring homework), but she excels in social situations . Interested in fashion (and little else), she was one of the most popular girls at her high school . Mandy is very confident and creative, demonstrating traits found in her father . She can be lazy, conceited, selfish, insulting, and delinquent--she drinks underage, ignores all driving laws, shoplifts from Outdoor Man, there are many implications that she smokes weed, and she has been caught staying out all night--but occasionally she displays moments of generosity and caring . She started dating Kyle in season 2 . As of season three, she attends a local college and works at the diner where Kristin used to work . Later that same season, she begins an online clothing business, selling her self - designed fashions which she assembles in the basement of her parents' house . Kyle asks her to marry him in season 5, the 100th episode . She marries Kyle in season six, but they have yet to move out of the Baxter home . Up until she turned 21, a running gag on the show was Mike, Vanessa, and occasionally Kristin snatching glasses of alcohol out of Mandy's hand, usually followed by Mandy making a lame excuse . </Li>

Who plays the oldest sister on last man standing