<Li> Chronic bullous dermatosis: a disease that causes clusters of blisters on the face, mouth or genitals . </Li> <Li> Cutaneous radiation syndrome </Li> <P> Friction blisters are caused by excess shear stress between the surface of the skin and the body . The strata of skin around the Stratum spinosum are most susceptible to shear . As the Stratum spinosum tears away from the connecting tissues below, plasma from the cells diffuses out . This plasma solution helps new cells divide and grow into new connective tissues and epidermal layers . </P> <P> The clear fluid will be reabsorbed as new cells develop and the swollen appearance will subside . Painful blisters located on hands (palmar surface) and feet (plantar surface) are due to tissue shearing deeper in the epidermis, near nerve endings . Lower tissues are more susceptible to infection . </P>

Where does the water come from in a blister
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