<P> Tentative evidence supports the use of amisulpride to treat dysthymia but with increased side effects . </P> <P> A combination of antidepressant medication and psychotherapy has consistently been shown to be the most effective line of treatment for people diagnosed with dysthymia . Working with a psychotherapist to address the causes and effects of the disorder, in addition to taking antidepressants to help eliminate the symptoms, can be extremely beneficial . This combination is often the preferred method of treatment for those who have dysthymia . Looking at various studies involving treatment for dysthymia, 75% of people responded positively to a combination of cognitive behavioral therapy (CBT) and pharmacotherapy, whereas only 48% of people responded positively to just CBT or medication alone . </P> <P> In a meta - analytic study from 2008, researchers found an effect size of −. 07 (Cohen's d) between pharmacologic treatments and psychological treatments for depressive disorders, suggesting pharmacologic treatments to be slightly more effective, though the results were not found to be statistically significant . This small effect is true only for SSRIs, with TCAs and other pharmacologic treatments showing no differences from psychological treatments . Additionally, there have been several studies yielding results that indicate that severe depression responds more favorably to psychotherapy than pharmacotherapy . </P> <P> Because of dysthymia's chronic nature, treatment resistance is somewhat common . In such a case, augmentation is often recommended . Such treatment augmentations can include lithium pharmacology, thyroid hormone augmentation, amisulpride, buspirone, bupropion, stimulants, and mirtazapine . Additionally, if the person also suffers from seasonal affective disorder, light therapy can be useful in helping augment therapeutic effects . </P>

Which of the following is a long-term disorder that is less severe than major depression