<Tr> <Th> Family </Th> <Td> Sloan Riley (daughter) Sofia Robbin Sloan Torres (daughter) Grandson (via Sloan) baby with Addison (aborted) </Td> </Tr> <Tr> <Th> Significant other (s) </Th> <Td> Lexie Grey (girlfriend, soulmate deceased) Addison Montgomery Callie Torres Teddy Altman Reed Adamson (deceased) Amelia Shepherd Julia Canner Nancy Shepherd </Td> </Tr> <P> Mark Everett Sloan, M.D., F.A.C.S. is a fictional character from ABC's medical drama television series Grey's Anatomy, portrayed by Eric Dane . Created by series producer Shonda Rhimes, the character was introduced in season two as Dr. Derek Shepherd's best friend who acted as the catalyst for the end of Shepherd's marriage when Shepherd caught Sloan sleeping with his wife, Dr. Addison Montgomery . Soon after moving to Seattle Grace Hospital as an attending specializing in plastic surgery to reconcile with Derek, Mark earned the nickname "McSteamy" for his good looks by the female interns . Mark's focal storyline in the series involved his romantic relationship with Dr. Lexie Grey . Both he and Lexie sustained life - threatening injuries after an aviation accident in the eighth season finale, which resulted in their deaths . Seattle Grace is later renamed Grey - Sloan Memorial Hospital in their memory . </P> <P> Mark first appears in season two, introduced as a highly respected otolaryngologist sub-specialized in plastic surgery and the childhood best friend of neurosurgeon Derek Shepherd (Patrick Dempsey). In his first appearance, he flirts with Meredith Grey, and Derek punches him in the face . Derek explains that Mark had an affair with his wife, Addison (Kate Walsh) while they were living in New York . Mark travels to Seattle, intent on convincing Addison to return with him, but his offer is rejected and Derek declines to renew their friendship . Mark returns during season three at Addison's drunken behest, but she again rejects him once sober . Undeterred, Mark sells his successful private practice (which he previously shared with Derek) and takes over the plastics program at Seattle Grace Hospital . During Meredith's morphine rampage, Mark finds out about his nickname McSteamy which was given to him by her during his first trip to Seattle back when he attempted to get Addison back and earn Derek's friendship back . It is later revealed that Mark has at some point slept with all of Derek's sisters . Mark has a brief fling with Addison's friend, orthopedic surgeon Callie Torres (Sara Ramirez), and develops a friendship with Derek's girlfriend, intern Meredith Grey (Ellen Pompeo). It is revealed that after Derek left New York, Mark and Addison continued their relationship for two months, during which she conceived and aborted his child . Just weeks after moving to Seattle he quickly observes that Derek's true love was Meredith and tries to convince Addison that her marriage with Derek was over . Mark enters into a sixty - day abstinence pact with Addison, agreeing that if they can remain celibate for that time, Addison will give their relationship another chance . Addison ultimately breaks the pact by having sex with intern Alex Karev (Justin Chambers), and soon thereafter departs from Seattle to work in Los Angeles . </P>

When does mark die in grey's anatomy