<P> Carter's Little Liver Pills (Carter's Little Pills after 1959) were formulated as a patent medicine by Samuel J. Carter of Erie, Pennsylvania, in 1868 . The active ingredient was changed when it was renamed in 1959 to be the laxative bisacodyl . </P> <P> Carter's trademark was a black crow . By 1880 the business was incorporated as Carter Products . The pills were touted to cure headache, constipation, dyspepsia, and biliousness . In the late 19th century, they were marketed in the UK by American businessman John Morgan Richards . </P> <P> Carter's Little Liver Pills predated the other available forms of bisacodyl and was a very popular and heavily advertised patent medicine up until the 1960s, spawning a common saying (with variants) in the first half of the 20th century: "He / She has more _________ than Carter has Little Liver Pills". In 1951 the Federal Trade Commission required the company to change the name to "Carter's Little Pills", since "liver" in the name was deceptive . </P>

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