<Tr> <Td_colspan="2"> (edit on Wikidata) </Td> </Tr> <P> Reye syndrome is a rapidly progressive encephalopathy . Symptoms may include vomiting, personality changes, confusion, seizures, and loss of consciousness . Even though liver toxicity typically occurs, yellowish skin usually does not . Death occurs in 20--40% of those affected and about a third of those who survive are left with a significant degree of brain damage . </P> <P> The cause of Reye syndrome is unknown . It usually begins shortly after recovery from a viral infection, such as influenza or chickenpox . About 90% of cases are associated with aspirin (salicylate) use in children . Inborn errors of metabolism are also a risk factor . Changes on blood tests may include a high blood ammonia level, low blood sugar level, and prolonged prothrombin time . Often the liver is enlarged . </P> <P> Prevention is typically by avoiding the use of aspirin in children . When aspirin was withdrawn for use in children a decrease of more than 90% in rates of Reye syndrome was seen . Early diagnosis improves outcomes . Treatment is supportive . Mannitol may be used to help with the brain swelling . </P>

An idiopathic condition associated with asprin treatment during certain viral infections