<P> Studies have found that Omalizumab (Xolair) may be an effective and safe treatment to cold urticaria for patient who do not sufficiently respond to standard treatments . </P> <P> Ebastine has been proposed as an approach to prevent acquired cold urticaria . </P> <Ul> <Li> Cold weather / Snow: Exposure to cold or cool air for more than a few minutes can trigger a reaction . </Li> <Li> Sweat: A reaction may even occur on a warm day when there is sweat on the skin . If there is a breeze it will rapidly cool the skin and create hives . </Li> <Li> Cold / Cool IV Lines: While in the hospital, inserting IV lines that have been refrigerated or are cool into individuals who are allergic to cold temperature can / may result in pain within the limb the IV is placed and a line of hives may appear within a radius of 6 - 8 inches from the IV site in the pattern of a line going up the limb . </Li> <Li> Swimming: Swimming can be especially dangerous as the rapid heart rate combined with the onset of hives can lead to hypotension . </Li> <Li> Air Conditioning: Entering a cool building during a summer day can result in an allergic reaction to exposed areas of skin, congestion from breathing the cool air and possibly feeling fatigued . </Li> <Li> Cold Foods / Drinks: Eating or drinking cold or cool substances such as ice cream or even iced tea may result in the individuals tongue and surrounding tissues swelling . </Li> <Li> Cool / Cold Surfaces: Sitting on sidewalks which are cool, leaning on or grabbing a cold pole will result in hives forming on the area which had contact with the cool surfaces . </Li> <Li> Restriction of Blood Flow: Typing or other activities which tense muscles and reduce blood flow can cool the body parts enough to cause itching and hives . </Li> <Li> Blood Flow: While putting hands or feet in hot water nails turn purple / white until the body gets used to the temperature . </Li> </Ul> <Li> Cold weather / Snow: Exposure to cold or cool air for more than a few minutes can trigger a reaction . </Li>

Skin itches when going from cold to hot