<Ul> <Li> Thin filaments consist primarily of the protein actin, coiled with nebulin filaments . Actin, when polymerized into filaments, forms the "ladder" along which the myosin filaments "climb" to generate motion </Li> <Li> Thick filaments consist primarily of the protein myosin, held in place by titin filaments . Myosin is responsible for force generation . It is composed of a globular head with both ATP and actin binding sites, and a long tail involved in its polymerization into myosin filaments . </Li> </Ul> <Li> Thin filaments consist primarily of the protein actin, coiled with nebulin filaments . Actin, when polymerized into filaments, forms the "ladder" along which the myosin filaments "climb" to generate motion </Li> <Li> Thick filaments consist primarily of the protein myosin, held in place by titin filaments . Myosin is responsible for force generation . It is composed of a globular head with both ATP and actin binding sites, and a long tail involved in its polymerization into myosin filaments . </Li> <P> The protein complex composed of actin and myosin is sometimes referred to as "actinomyosin". </P>

Site where support proteins hold thick filaments together
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