<Li> Bacteria, Archaea, fungi and parasites release membrane vesicles (MVs) containing varied but specialized toxic compounds and biochemical signal molecules, which are transported to target cells to initiate processes in favour of the microbe, which include invasion of host cells and killing of competing microbes in the same niche . </Li> <P> Extracellular vesicles (EVs) are produced by all domains of life including complex eukaryotes, both Gram - negative and Gram - positive bacteria, mycobacteria and fungi . </P> <Ul> <Li> Exosomes: membraneous vesicles of endocytic origin (50 - 100 nm diameter) enriched in CD63 and CD81 . </Li> <Li> microvesicle (also referred to as shedding microvesicles, SMVs), that are shed directly from the plasma membrane (20--1000 nm). </Li> <Li> membrane particles (50--80 nm), or large membranous vesicles (~ 600 nm) CD133, CD63 </Li> <Li> Apoptotic blebs or blebbing vesicles (1000--5000 nm diameter): released by dying cells . </Li> </Ul> <Li> Exosomes: membraneous vesicles of endocytic origin (50 - 100 nm diameter) enriched in CD63 and CD81 . </Li>

Where do the vesicles that are being made