<P> In general, thermodynamic analysis of solutions is done by modeling them as reactions . For example, if you add sodium chloride to water, the salt will dissociate into the ions sodium (+ aq) and chloride (- aq). The equilibrium constant for this dissociation can be predicted by the change in Gibbs energy of this reaction . </P> <P> The Born equation is used to estimate Gibbs free energy of solvation of a gaseous ion . </P> <Table> <Tr> <Td> </Td> <Td> (hide) This section has multiple issues . Please help improve it or discuss these issues on the talk page . (Learn how and when to remove these template messages) <Table> <Tr> <Td> </Td> <Td> This section needs expansion with: basic concepts of solvation and biomolecule intramolecular interactions and folding, and their intermolecular interactions, including such things as DNA - protein and protein - protein interactions, and small molecule binding, and formation of biologic macromolecular assemblies . You can help by adding to it . (June 2015) </Td> </Tr> </Table> <Table> <Tr> <Td> </Td> <Td> This section only describes one highly specialized aspect of its associated subject . Please help improve this article by adding more general information . The talk page may contain suggestions . (June 2015) </Td> </Tr> </Table> (Learn how and when to remove this template message) </Td> </Tr> </Table> <Tr> <Td> </Td> <Td> (hide) This section has multiple issues . Please help improve it or discuss these issues on the talk page . (Learn how and when to remove these template messages) <Table> <Tr> <Td> </Td> <Td> This section needs expansion with: basic concepts of solvation and biomolecule intramolecular interactions and folding, and their intermolecular interactions, including such things as DNA - protein and protein - protein interactions, and small molecule binding, and formation of biologic macromolecular assemblies . You can help by adding to it . (June 2015) </Td> </Tr> </Table> <Table> <Tr> <Td> </Td> <Td> This section only describes one highly specialized aspect of its associated subject . Please help improve this article by adding more general information . The talk page may contain suggestions . (June 2015) </Td> </Tr> </Table> (Learn how and when to remove this template message) </Td> </Tr>

Which factors can affect the rate of solvation