<Li> Hypoestrogenism and melatonin supplementation increase cortisol levels in postmenopausal women . </Li> <Li> Severe trauma or stressful events can elevate cortisol levels in the blood for prolonged periods . </Li> <Li> Subcutaneous adipose tissue regenerates cortisol from cortisone by the enzyme 11 - beta HSD1 . </Li> <Li> Anorexia nervosa may be associated with increased cortisol levels . </Li>

As anti-inflammatory medications the main mechanism of action of cortisol and corticosterone is