<Ol> <Li> Membrane blebbing: The cell membrane shows irregular buds known as blebs . Initially these are smaller surface blebs . Later these can grow into larger so - called dynamic membrane blebs . An important regulator of apoptotic cell membrane blebbing is ROCK1 (rho associated coiled - coil - containing protein kinase 1). </Li> <Li> Formation of membrane protrusions: Some cell types, under specific conditions, may develop different types of long, thin extensions of the cell membrane called membrane protrusions . Three types have been described: microtubule spikes, apoptopodia (feet of death), and beaded apoptopodia (the latter having a beads - on - a-string appearance). Pannexin 1 is an important component of membrane channels involved in the formation of apoptopodia and beaded apoptopodia . </Li> <Li> Fragmentation: The cell breaks apart into multiple vesicles called apoptotic bodies, which undergo phagocytosis . The plasma membrane protrusions may help bring apoptotic bodies closer to phagocytes . </Li> </Ol> <Li> Membrane blebbing: The cell membrane shows irregular buds known as blebs . Initially these are smaller surface blebs . Later these can grow into larger so - called dynamic membrane blebs . An important regulator of apoptotic cell membrane blebbing is ROCK1 (rho associated coiled - coil - containing protein kinase 1). </Li> <Li> Formation of membrane protrusions: Some cell types, under specific conditions, may develop different types of long, thin extensions of the cell membrane called membrane protrusions . Three types have been described: microtubule spikes, apoptopodia (feet of death), and beaded apoptopodia (the latter having a beads - on - a-string appearance). Pannexin 1 is an important component of membrane channels involved in the formation of apoptopodia and beaded apoptopodia . </Li> <Li> Fragmentation: The cell breaks apart into multiple vesicles called apoptotic bodies, which undergo phagocytosis . The plasma membrane protrusions may help bring apoptotic bodies closer to phagocytes . </Li>

What does the healthy version of the cell membrane protein do