<P> Writers of Sporting News described hitting four home runs in a single Major League Baseball (MLB) game as "baseball's greatest single - game accomplishment". Seventeen players have accomplished the feat to date, the most recent being Scooter Gennett of the Cincinnati Reds on June 6, 2017 against the St. Louis Cardinals . No player has done this more than once in his career and no player has ever hit more than four in a game . Bobby Lowe was the first to hit four home runs in a single game, doing so on May 30, 1894 . Fans were reportedly so excited that they threw $160 in silver coins ($4,400 today) onto the field after his fourth home run . </P> <P> These games have resulted in other MLB single - game records due to the extreme offensive performance . Mark Whiten, for example, tied Jim Bottomley for the most runs batted in in a single game with 12 in his four - homer game . Shawn Green hit a double and a single along with his four home runs for 19 total bases, an MLB record . It surpassed Joe Adcock's mark of 18, which also came from a four - homer game . </P>

Most home runs by a single player in one game