<Tr> <Th_colspan="2"> External links </Th> </Tr> <Tr> <Th> Official website </Th> <Td> abc.go.com/shows/greys-anatomy </Td> </Tr> <P> Grey's Anatomy is an American medical drama television series that premiered on American Broadcasting Company (ABC) as a mid-season replacement on March 27, 2005 . The series focuses on the fictional lives of surgical interns, residents, and attending physicians, as they evolve into seasoned doctors while trying to maintain personal lives and relationships . The title is a play on Gray's Anatomy, a classic human anatomy textbook by Henry Gray . </P> <P> The show's premise originated with creator Shonda Rhimes, who serves as an executive producer, along with Betsy Beers, Mark Gordon, Krista Vernoff, Rob Corn, Mark Wilding, and Allan Heinberg . Although it is set in Seattle (at the fictional Grey - Sloan Memorial Hospital, formerly Seattle Grace), it is primarily filmed in Los Angeles, California . The show was originally titled Complications, a reference to the complicated medical procedures and personal lives of the characters . </P>

When did the first season of greys anatomy air