<P> Key West is 129 miles (208 km) southwest of Miami by air, about 160 miles (260 km) by car, and 106 miles (171 km) north - northeast of Havana, Cuba . Cuba, at its closest point, is 94 miles (151 km) south . Key West is a port of call for many passenger cruise ships . The Key West International Airport provides airline service . Naval Air Station Key West is an important year round training site for naval aviation due to the tropical weather, which is also the reason Key West was chosen as the Winter White House of President Harry S. Truman . The central business district is located along Duval Street and includes much of the northwestern corner of the island . The official city motto is "One Human Family ." </P> <P> In Pre-Colonial times Key West was inhabited by the Calusa people . The first European to visit was Juan Ponce de León in 1521 . As Florida became a Spanish territory, a fishing and salvage village with a small garrison was established here . </P> <P> Cayo Hueso (Spanish pronunciation: (ˈkaʝo ˈweso)) is the original Spanish name for the island of Key West . Spanish - speaking people today also use the term when referring to Key West . It literally means "bone cay (a low island or reef)". It is said that the island was littered with the remains (bones) of prior native inhabitants, who used the isle as a communal graveyard . This island was the westernmost Key with a reliable supply of water . </P> <P> In 1763, when Great Britain took control of Florida, the community of Spaniards and Native Americans were moved to Havana . Florida returned to Spanish control 20 years later, but there was no official resettlement of the island . Informally the island was used by fishermen from Cuba and from the British, who were later joined by others from the United States after the latter nation's independence . While claimed by Spain, no nation exercised de facto control over the community there for some time . </P>

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