<Tr> <Td_colspan="2"> The Season 6 Promotional Photo of Katherine Heigl as Dr. Izzie Stevens </Td> </Tr> <Tr> <Th> First appearance </Th> <Td> "A Hard Day's Night" 1x01, March 27, 2005 </Td> </Tr> <Tr> <Th> Last appearance </Th> <Td> "I Like You So Much Better When You're Naked" 6x12, January 21, 2010 </Td> </Tr> <Tr> <Th> Created by </Th> <Td> Shonda Rhimes </Td> </Tr>

In what episode of grey's anatomy does izzy get cancer