<Li> Type 2 (early postoperative infection): Infection occurring within first month after surgery </Li> <Li> Type 3 (acute hematogenous infection): Hematogenous seeding of site of previously well - functioning prosthesis </Li> <Li> Type 4 (late chronic infection): Chronic indolent clinical course; infection present for more than a month </Li> <P> While it is relatively rare, periprosthetic infection remains one of the most challenging complications of joint arthroplasty . A detailed clinical history and physical remain the most reliable tool to recognize a potential periprosthetic infection . In some cases the classic signs of fever, chills, painful joint, and a draining sinus may be present, and diagnostic studies are simply done to confirm the diagnosis . In reality though, most patients do not present with those clinical signs, and in fact the clinical presentation may overlap with other complications such as aseptic loosening and pain . In those cases diagnostic tests can be useful in confirming or excluding infection . </P>

When was the first total knee replacement done