<Li> Bizarre cells, which are multinucleated . </Li> <Li> Mott cells, containing multiple clustered cytoplasmic droplets or other inclusions (sometimes confused with auer rods, commonly seen in myeloid blasts) </Li> <Li> Flame cells, having a fiery red cytoplasm . </Li> <P> Historically, the CD138 has been used to isolate myeloma cells for diagnostic purposes . However, this antigen disappears rapidly ex vivo . Recently, however, it was discovered that the surface antigen CD319 (SLAMF7) is considerably more stable and allows robust isolation of malignant plasma cells from delayed or even cryopreserved samples . </P>

A malignant tumor of plasma cells in the bone marrow is called