<P> Most people have just one pancreatic duct . However, some have an additional accessory pancreatic duct, called the Duct of Santorini . An accessory pancreatic duct can be functional or non-functional and may open separately into the second part of the duodenum which is dorsal and usually (in 70%) drains into to the duodenum via the minor duodenal papilla . In the other 30% it drains into the main pancreatic duct, which drains into the duodenum via the major duodenal papilla . The main pancreatic duct and the accessory duct both eventually - either directly or indirectly - connect to the second part (' D2', the vertical segment) of the duodenum . </P> <P> It is named for Giovanni Domenico Santorini . </P> <P> Compression, obstruction or inflammation of the pancreatic duct may lead to acute pancreatitis . The most common cause for obstruction is the presence of gallstones in the common bile duct, a condition called choledocholithiasis . Obstruction can also be due to duodenal inflammation in Crohn's disease . A gallstone may get lodged in the constricted distal end of the ampulla of Vater, where it blocks the flow of both bile and pancreatic juice into the duodenum . Bile backing up into the pancreatic duct may initiate pancreatitis . The pancreatic duct is generally regarded as abnormally enlarged if being over 3 mm in the head and 2 mm in the body or tail . </P> <P> Pancreatic ductal carcinoma is a common form of pancreatic cancer . </P>

Where does the pancreatic duct enter the gi tract