<Tr> <Td_colspan="2"> Anatomical terms of neuroanatomy (edit on Wikidata) </Td> </Tr> <P> The primary motor cortex (Brodmann area 4) is a brain region that in humans is located in the dorsal portion of the frontal lobe . It is the primary region of the motor system and works in association with other motor areas including premotor cortex, the supplementary motor area, posterior parietal cortex, and several subcortical brain regions, to plan and execute movements . Primary motor cortex is defined anatomically as the region of cortex that contains large neurons known as Betz cells . Betz cells, along with other cortical neurons, send long axons down the spinal cord to synapse onto the interneuron circuitry of the spinal cord and also directly onto the alpha motor neurons in the spinal cord which connect to the muscles . </P> <P> At the primary motor cortex, motor representation is orderly arranged (in an inverted fashion) from the toe (at the top of the cerebral hemisphere) to mouth (at the bottom) along a fold in the cortex called the central sulcus . However, some body parts may be controlled by partially overlapping regions of cortex . Each cerebral hemisphere of the primary motor cortex only contains a motor representation of the opposite (contralateral) side of the body . The amount of primary motor cortex devoted to a body part is not proportional to the absolute size of the body surface, but, instead, to the relative density of cutaneous motor receptors on said body part . The density of cutaneous motor receptors on the body part is generally indicative of the necessary degree of precision of movement required at that body part . For this reason, the human hands and face have a much larger representation than the legs . </P> <P> For the discovery of the primary motor cortex and its relationship to other motor cortical areas, see the main article on the motor cortex . </P>

The map size in the motor cortex is proportional to