<Dd> α - ketoglutarate + NAD + CoA → Succinyl CoA + CO + NADH </Dd> <P> This reaction proceeds in three steps: </P> <Ul> <Li> decarboxylation of α - ketoglutarate, </Li> <Li> reduction of NAD to NADH, </Li> <Li> and subsequent transfer to CoA, which forms the end product, succinyl CoA . </Li> </Ul> <Li> decarboxylation of α - ketoglutarate, </Li>

Conversion of α-ketoglutarate to succinyl-coa catalyzed by α-ketoglutarate dehydrogenase complex