<P> The series follows 7th grade best friends Nick Birch and Andrew Glouberman as they navigate their way through puberty, masturbation, and sexual arousal . Acting as sex - based shoulder angels are the hormone monsters; Maurice (who pesters Andrew and occasionally Nick and Jay, and strongly resembles Pan), and Connie (who pesters Jessi and occasionally Missy). Throughout the series, the kids interact with people and objects who are personified in one way or another and offer helpful, albeit confusing, advice in their puberty - filled lives including the ghost of Duke Ellington, a French accented Statue of Liberty, a pillow capable of getting pregnant, and even Jessi's own vagina . </P> <Ul> <Li> Nick Kroll as: <Ul> <Li> Nick Birch, an almost - adolescent boy living with loving and overprotective parents . He also has an older brother named Judd and an older sister named Leah . </Li> <Li> Maurice the Hormone Monster, a wild thing - type monster who follows Andrew around and is responsible for his brooding sexual desires, which frequently occur at inappropriate moments . </Li> <Li> Coach Steve, the middle school gym class teacher, who is incompetent and overly talkative, often trying to get his colleagues--or even the students--to hang out (often to no avail). It is heavily implied that the coach may be mentally disabled; he cannot read . </Li> <Li> Kroll also voices Lola, Lady Liberty, a ladybug, Joe Walsh, the ghosts of Picasso and Richard Burton, and Sylvester Stallone . </Li> </Ul> </Li> <Li> John Mulaney as Andrew Glouberman, a young Jewish boy, who spends much of his time furtively masturbating . <Ul> <Li> Mulaney also voices Mint, Grandpa Andrew, Babe the Blue Ox, and a detective . </Li> </Ul> </Li> <Li> Jessi Klein as Jessi Glaser, a sarcastic and smart girl and Nick's love interest . Her father, named Greg, is an unemployed stoner and her mother, named Shannon, is secretly dating another woman . She gets her period for the first time on a school trip to the Statue of Liberty . Though Jessi has kissed Nick before, specifically in the first episode "Ejaculation", she has had many make - out sessions or flings with Jay as to French kiss him . She, like Andrew, is Jewish, as she had a Bat Mitzvah in episode 9, "I Survived Jessi's Bat Mizvah". </Li> <Li> Jason Mantzoukas as Jay Bilzerian, a boy who is obsessed with magic and sex . He has sex with a pillow that he made into a sex toy . His mom is mentally ill, his dad is a divorce lawyer, and his two older brothers are named Kurt and Val . He is obsessed with Nick's mother and father and wishes for a loving family . <Ul> <Li> Mantzoukas also voices the ghost of Socrates and Guy Bilzerian . </Li> </Ul> </Li> <Li> Jenny Slate as Missy, a girl who is nerdy and kind . Her father is black and her mother is Mexican . </Li> <Li> Fred Armisen as Elliot Birch, Nick's loving father, who frequently shares inappropriate stories . <Ul> <Li> Armisen also voices the ghost of Antonin Scalia, a bus driver, and Stavros . </Li> </Ul> </Li> <Li> Maya Rudolph as: <Ul> <Li> Diane Birch, Nick's loving mother, who babies him . </Li> <Li> Connie the Hormone Monstress, who follows Jessi around and encourages her to embrace her wildest desires . </Li> <Li> Rudolph also voices a bath mat and the ghosts of Elizabeth Taylor and Whitney Houston . </Li> </Ul> </Li> <Li> Jordan Peele as the Ghost of Duke Ellington, the late jazz musician whose spirit now lives in Nick's attic and sometimes offers him advice . <Ul> <Li> Peele also voices the ghost of Freddie Mercury, Atlanta Claus, a DJ, Missy's father Cyrus, and Patrick Ewing . </Li> </Ul> </Li> </Ul> <Li> Nick Kroll as: <Ul> <Li> Nick Birch, an almost - adolescent boy living with loving and overprotective parents . He also has an older brother named Judd and an older sister named Leah . </Li> <Li> Maurice the Hormone Monster, a wild thing - type monster who follows Andrew around and is responsible for his brooding sexual desires, which frequently occur at inappropriate moments . </Li> <Li> Coach Steve, the middle school gym class teacher, who is incompetent and overly talkative, often trying to get his colleagues--or even the students--to hang out (often to no avail). It is heavily implied that the coach may be mentally disabled; he cannot read . </Li> <Li> Kroll also voices Lola, Lady Liberty, a ladybug, Joe Walsh, the ghosts of Picasso and Richard Burton, and Sylvester Stallone . </Li> </Ul> </Li> <Ul> <Li> Nick Birch, an almost - adolescent boy living with loving and overprotective parents . He also has an older brother named Judd and an older sister named Leah . </Li> <Li> Maurice the Hormone Monster, a wild thing - type monster who follows Andrew around and is responsible for his brooding sexual desires, which frequently occur at inappropriate moments . </Li> <Li> Coach Steve, the middle school gym class teacher, who is incompetent and overly talkative, often trying to get his colleagues--or even the students--to hang out (often to no avail). It is heavily implied that the coach may be mentally disabled; he cannot read . </Li> <Li> Kroll also voices Lola, Lady Liberty, a ladybug, Joe Walsh, the ghosts of Picasso and Richard Burton, and Sylvester Stallone . </Li> </Ul>

Who plays the hormone monster in big mouth