<P> Dax (Lil Rel Howery) convinces former basketball playground legend Uncle Drew (Kyrie Irving) to join a street ball tournament at the Rucker Park in Harlem after losing his basketball team to his rival Mookie (Nick Kroll). Uncle Drew agrees but as one of the conditions, he will have to form his own team . The two set out on a road trip to pick up Drew's old basketball squad . </P> <Ul> <Li> Kyrie Irving as Uncle Drew, a streetball legend . </Li> <Li> Lil Rel Howery as Dax, a streetball team manager . <Ul> <Li> Ashton Tyler as Young Dax </Li> </Ul> </Li> <Li> Shaquille O'Neal as Big Fella, Uncle Drew's former teammate who now runs a martial - arts dojo . </Li> <Li> Chris Webber as Preacher, Uncle Drew's former teammate who is now a church minister </Li> <Li> Reggie Miller as Lights, Uncle Drew's former teammate who presently seems to be legally blind . </Li> <Li> Nate Robinson as Boots, Uncle Drew's former teammate who now lives in a retirement home . </Li> <Li> Lisa Leslie as Betty Lou </Li> <Li> Erica Ash as Maya </Li> <Li> JB Smoove as Angelo </Li> <Li> Mike Epps </Li> <Li> Tiffany Haddish as Jess </Li> <Li> Nick Kroll as Mookie, Dax's longtime rival . </Li> <Li> Aaron Gordon </Li> </Ul> <Li> Kyrie Irving as Uncle Drew, a streetball legend . </Li> <Li> Lil Rel Howery as Dax, a streetball team manager . <Ul> <Li> Ashton Tyler as Young Dax </Li> </Ul> </Li>

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