<Li> cornified layer (stratum corneum) </Li> <Dl> <Dd> <Dl> <Dd> Composed of 10 to 30 layers of polyhedral, anucleated corneocytes (final step of keratinocyte differentiation), with the palms and soles having the most layers . Corneocytes are surrounded by a protein envelope (cornified envelope proteins), filled with water - retaining keratin proteins, attached together through corneodesmosomes and surrounded in the extracellular space by stacked layers of lipids . Most of the barrier functions of the epidermis localize to this layer . </Dd> </Dl> </Dd> </Dl> <Dd> <Dl> <Dd> Composed of 10 to 30 layers of polyhedral, anucleated corneocytes (final step of keratinocyte differentiation), with the palms and soles having the most layers . Corneocytes are surrounded by a protein envelope (cornified envelope proteins), filled with water - retaining keratin proteins, attached together through corneodesmosomes and surrounded in the extracellular space by stacked layers of lipids . Most of the barrier functions of the epidermis localize to this layer . </Dd> </Dl> </Dd> <Dl> <Dd> Composed of 10 to 30 layers of polyhedral, anucleated corneocytes (final step of keratinocyte differentiation), with the palms and soles having the most layers . Corneocytes are surrounded by a protein envelope (cornified envelope proteins), filled with water - retaining keratin proteins, attached together through corneodesmosomes and surrounded in the extracellular space by stacked layers of lipids . Most of the barrier functions of the epidermis localize to this layer . </Dd> </Dl>

Most common type of cell in the epidermis