<Tr> <Th> PubMed </Th> <Td> articles </Td> </Tr> <Tr> <Th> NCBI </Th> <Td> proteins </Td> </Tr> <P> Botulinum toxin (BTX) or Botox is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species . It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction and thus causes flaccid paralysis . Infection with the bacterium causes the disease botulism . The toxin is also used commercially in medicine, cosmetics and research . </P> <P> Botulinum is the most acutely lethal toxin known, with an estimated human median lethal dose (LD) of 1.3--2.1 ng / kg intravenously or intramuscularly and 10--13 ng / kg when inhaled . </P>

Where does botulinum toxin type h come from