<P> Antibiotic treatments for one to three days shorten the course of the disease and reduce the severity of the symptoms . Use of antibiotics also reduces fluid requirements . People will recover without them, however, if sufficient hydration is maintained . The World Health Organization only recommends antibiotics in those with severe dehydration . </P> <P> Doxycycline is typically used first line, although some strains of V. cholerae have shown resistance . Testing for resistance during an outbreak can help determine appropriate future choices . Other antibiotics proven to be effective include cotrimoxazole, erythromycin, tetracycline, chloramphenicol, and furazolidone . Fluoroquinolones, such as ciprofloxacin, also may be used, but resistance has been reported . </P> <P> Antibiotics improve outcomes in those who are both severely and not severely dehydrated . Azithromycin and tetracycline may work better than doxycycline or ciprofloxacin . </P> <P> In Bangladesh zinc supplementation reduced the duration and severity of diarrhea in children with cholera when given with antibiotics and rehydration therapy as needed . It reduced the length of disease by eight hours and the amount of diarrhea stool by 10% . Supplementation appears to be also effective in both treating and preventing infectious diarrhea due to other causes among children in the developing world . </P>

What does boiling water do to protein of any bacteria that might be present