<Ul> <Li> I ‐ 4, which spans 133 miles, bisects the state, connecting Tampa, Lakeland, Orlando, and Daytona Beach, connecting with I - 75 in Tampa and I - 95 in Daytona Beach . </Li> <Li> I - 10, which spans 362 miles in Florida, traverses the panhandle, connecting Pensacola, Tallahassee, Lake City, and Jacksonville, with interchanges with I - 75 in Lake City and I - 95 in Jacksonville . It is the southernmost interstate in the United States terminating in Santa Monica with a total length of 2460 miles . </Li> <Li> I - 75, which spans 470 miles in Florida, enters the state near Lake City (45 miles (72 km) west of Jacksonville) and continues southward through Gainesville, Ocala, Tampa's eastern suburbs, Bradenton, Sarasota, Fort Myers and Naples, where it crosses the "Alligator Alley" as a toll road to Fort Lauderdale before turning southward and terminating in Hialeah / Miami Lakes having interchanges with I - 10 in Lake City and I - 4 in Tampa . It is the second longest north south interstate with a total length of 1786 miles and terminates at the Canadian border at Sault Ste . Marie, Michigan . </Li> <Li> I - 95, which spans 382 miles in Florida, enters the state near Jacksonville and continues along the Atlantic Coast through Daytona Beach, the Melbourne / Titusville, Palm Bay, Vero Beach, Fort Pierce, Port Saint Lucie, Stuart, West Palm Beach, and Fort Lauderdale, before terminating in Downtown Miami, with interchanges with I - 10 in Jacksonville and I - 4 in Daytona Beach . There are four auxiliary routes associated with the interstate . It is the longest north south interstate with a total length of 1924 miles and terminates at the Canadian border northeast of Houlton, Maine . </Li> </Ul> <Li> I ‐ 4, which spans 133 miles, bisects the state, connecting Tampa, Lakeland, Orlando, and Daytona Beach, connecting with I - 75 in Tampa and I - 95 in Daytona Beach . </Li> <Li> I - 10, which spans 362 miles in Florida, traverses the panhandle, connecting Pensacola, Tallahassee, Lake City, and Jacksonville, with interchanges with I - 75 in Lake City and I - 95 in Jacksonville . It is the southernmost interstate in the United States terminating in Santa Monica with a total length of 2460 miles . </Li> <Li> I - 75, which spans 470 miles in Florida, enters the state near Lake City (45 miles (72 km) west of Jacksonville) and continues southward through Gainesville, Ocala, Tampa's eastern suburbs, Bradenton, Sarasota, Fort Myers and Naples, where it crosses the "Alligator Alley" as a toll road to Fort Lauderdale before turning southward and terminating in Hialeah / Miami Lakes having interchanges with I - 10 in Lake City and I - 4 in Tampa . It is the second longest north south interstate with a total length of 1786 miles and terminates at the Canadian border at Sault Ste . Marie, Michigan . </Li>

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