<Li> Lifestyle disease such as cardiovascular disease, diseases caused by substance abuse such as alcoholism, and smoking - related disease </Li> <Li> Disease caused by physical factors in the environment, such as skin cancer caused by excessive exposure to ultraviolet radiation in sunlight </Li> <Li> Disease caused by exposure to toxic or irritant chemicals in the environment such as toxic metals </Li> <P> Environmental diseases are a direct result from the environment . This includes diseases caused by substance abuse, exposure to toxic chemicals, and physical factors in the environment, like UV radiation from the sun, as well as genetic predisposition . Meanwhile, pollution - related diseases are attributed to exposure to toxins in the air, water, and soil . Therefore all pollution - related disease are environmental diseases, but not all environmental diseases are pollution - related diseases . </P>

List two factors of heredity and two factors of environmental exposures in the role of disease