<P> Jeff Yagher was originally cast as Officer Tom Hanson in the pilot . He was replaced after the original pilot episode was filmed, and his scenes were reshot with Johnny Depp . Midway through the first season, Frederic Forrest was replaced by Steven Williams . On the show, Forrest's character Richard Jenko is killed by a drunk driver . Johnny Depp left the series at the end of the fourth season, but was credited in the first two episodes of the fifth season, despite not having appeared . </P> <P> Some notable guest stars on the series include: Dom DeLuise, Josh Brolin, Mindy Cohn, Bridget Fonda, Bobby Rodriguez, Jada Pinkett Smith, Brad Pitt, Vince Vaughn, Blair Underwood, John Waters, Rosie Perez, Kareem Abdul - Jabbar, Mario Van Peebles, Christina Applegate, Pauly Shore, David DeLuise, Bradley Gregg, Jason Priestley, Christopher Titus, Sarah Buxton, David Paymer, Diedrich Bader, Russell Wong, Kelly Hu, Shannon Tweed, and Peter Berg . </P> <P> Set in a fictional city and state (Metropolis, Evergreen State) in the United States, the series was primarily filmed in Vancouver, British Columbia . It was one of the first major television series to use Vancouver as a filming location and helped to establish the city as a center for film production . </P> <P> 21 Jump Street, along with Married...with Children and The Tracey Ullman Show, debuted in the spring of 1987 . All three shows were hits with audiences and helped to establish the then - newly launched Fox network . 21 Jump Street was the first hit series for the Fox network . In August, 21 Jump Street became the first Fox series to win its timeslot against a Big three network series . In the United Kingdom, it was shown on the similarly nascent, and interrelated, Sky One, which had yet to reach a sizeable audience . </P>

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