<Li> Several nucleases that degrade nucleic acids, like DNAase and RNAase </Li> <Li> Pancreatic amylase that breaks down starch and glycogen which are alpha - linked glucose polymers . Humans lack the cellulases to digest the carbohydrate cellulose which is a beta - linked glucose polymer . </Li> <P> Pancreas's exocrine function owes part of its immaculate function to bio-feedback mechanisms controlling secretion of its juice . The following significant pancreatic bio-feedback mechanisms are essential to the maintenance of pancreatic juice balance / production: </P> <Ul> <Li> Secretin, a hormone produced by the duodenal "S cells" in response to the stomach chyme containing high hydrogen atom concentration (high acidicity), is released into the blood stream; upon return to the digestive tract, secretion decreases gastric emptying, increases secretion of the pancreatic ductal cells, as well as stimulating pancreatic acinar cells to release their zymogenic juice . </Li> <Li> Cholecystokinin (CCK) is a unique peptide released by the duodenal "I cells" in response to chyme containing high fat or protein content . Unlike secretin, which is an endocrine hormone, CCK actually works via stimulation of a neuronal circuit, the end - result of which is stimulation of the acinar cells to release their content . CCK also increases gallbladder contraction, resulting in bile squeezed into the cystic duct, common bile duct and eventually the duodenum . Bile of course helps absorption of the fat by emulsifying it, increasing its absorptive surface . Bile is made by the liver, but is stored in the gallbladder . </Li> <Li> Gastric inhibitory peptide (GIP) is produced by the mucosal duodenal cells in response to chyme containing high amounts of carbohydrate, proteins, and fatty acids . Main function of GIP is to decrease gastric emptying . </Li> <Li> Somatostatin is a hormone produced by the mucosal cells of the duodenum and also the "delta cells" of the pancreas . Somatostatin has a major inhibitory effect, including on pancreatic production . </Li> </Ul>

Where is protease secreted in the digestive system