<Li> Key: PPZMYIBUHIPZOS - UHFFFAOYSA - N </Li> <P> Histamine dihydrochloride (INN, trade name Ceplene) is a salt of histamine which is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML). </P> <P> It is a FDA - approved active ingredient for topical analgesic use and is available in such products as Australian Dream Cream, which is used for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, sprains, and strains . </P> <P> Histamine dihydrochloride is administered in conjunction with low doses of the immune - activating cytokine interleukin - 2 (IL - 2) in the post-remission phase of AML, i.e. when patients have completed the initial chemotherapy . This combination has been reported to significantly reduce the risk of relapse in AML . The effect is particularly pronounced in patients in their first remission who are below the age of 60 . </P>

What is the active ingredient in australian dream cream
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