<P> Alex Borstein voices Lois Griffin, Asian correspondent Tricia Takanawa, Loretta Brown and Lois' mother Barbara Pewterschmidt . Borstein was asked to provide a voice for the pilot while she was working on MADtv . She had not met MacFarlane or seen any of his artwork and said it was "really sight unseen". At the time, Borstein performed in a stage show in Los Angeles, in which she played a redhead mother whose voice she had based on one of her cousins . The voice was originally slower (and deeper for the original series), but when MacFarlane heard it, he replied "Make it a little less fucking annoying...and speed it up, or every episode will last four hours ." </P> <P> Mila Kunis voices Meg Griffin . Kunis won the role after auditions and a slight rewrite of the character, in part due to her performance on That' 70s Show . MacFarlane called Kunis back after her first audition, instructing her to speak slower, and then told her to come back another time and enunciate more . Once she claimed that she had it under control, MacFarlane hired her . Kunis described her character as "the scapegoat". She further explained, "Meg gets picked on a lot . But it's funny . It's like the middle child . She is constantly in the state of being an awkward 14 - year - old, when you're kind of going through puberty and what - not . She's just in a perpetual mode of humiliation . And it's fun ." </P> <P> Seth Green primarily plays Chris Griffin and Neil Goldman . Green stated that he did an impression of the "Buffalo Bill" character from the thriller film The Silence of the Lambs during his audition . His main inspiration for Chris' voice came from envisioning how "Buffalo Bill" would sound if he were speaking through a public address system at a McDonald's . </P> <P> Mike Henry is the voice of Cleveland Brown, John Herbert The Pervert and various other characters . A Family Guy writer and producer, he began acting on the show as part of the recurring cast repertory (see below) but was promoted to main cast member in 2005 . Since the cancellation of The Cleveland Show, he also voices Cleveland's step - son Rallo Tubbs on Family Guy . </P>

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