<P> In Season 2, Lucas and Keith return to Tree Hill after Dan has a heart attack . Lucas tries to make up for his behavior with Peyton and Brooke and becomes friends with both of them . He also starts seeing a new girl named Anna Taggaro, but they break up amicably when Anna accepts that she is a lesbian . Lucas realizes that he has romantic feelings for Brooke and begins to focus on building on a relationship with her, even though she is seeing Anna's brother Felix . Lucas discovers that he has inherited Dan's heart condition, but does not tell anyone except Dan . After discovering that Keith's new girlfriend Jules was actually hired by Dan to break Keith's heart, Lucas agrees to move in with Dan if he leaves Keith alone and pays for Lucas's heart medication . This sets Lucas at odds with his mother, as she cannot believe that Lucas would want to live with Dan rather than her . It also causes a new rift between Lucas and Nathan, as Nathan feels that Lucas is replacing him and is bitter about Haley's departure to go on tour singing . Lucas and Karen are reconciled when she learns half of the reason he is staying with Dan, which is to protect Keith . This plan to protect his uncle fails when Jules leaves Keith at the altar and Keith leaves town after discovering that Lucas and Karen knew that she was hired by Dan . Lucas discovers Deb's painkiller addiction and decides to avenge all of Dan's victims . He finds a stash of cash and an incriminating ledger in the attic at Dan's dealership and plans to expose Dan's illegal dealings, but ultimately fails as Dan has also incriminated Deb . Dan then reveals that the whole thing was a set - up to test Lucas's loyalty, which Lucas failed . As a result, he loses Dan's college fund for him (which Dan had been saving since Lucas was a baby) and even his heart medication . Nathan also ends his friendship with Lucas after discovering that Lucas had planned to bring Dan down and visited Haley behind his back in an attempt to patch up her and Nathan's marriage . Lucas does, however, kiss Brooke in the season finale and confesses that he wants to be with her, but she still leaves for California to spend the summer with her parents . Ultimately, it is just Lucas and a broken - hearted Peyton (after boyfriend Jake left her) for the summer and the last shot is of the two of them sharing a meaningful hug on the beach . </P> <P> In Season 3, after the summer, Lucas remains at odds with Dan, who accuses Lucas of starting the fire at the dealership that nearly killed him . Dan tries to strangle Lucas on the basketball court, but Peyton, having learned the truth from Lucas, tells Dan that Lucas actually saved him from the fire . Lucas also protects the true arsonist: Deb . Lucas and Nathan continue to argue over Nathan's treatment of the returned Haley and have a public fight after Lucas accuses Nathan of being just like Dan . Lucas struggles to pay for his heart medication and steals money from his mother, which Haley sees, forcing Lucas to tell her about his condition . He begins a non-exclusive relationship with Brooke and uses Rachel Gatina to make her jealous, but a series of events leads Brooke to sleep with Chris Keller, tearing them apart . Later, he forgives her after she gives him the 82 letters she wrote to him during her vacation but did not send . He and Nathan gradually become friends again . Keith returns, and he and Karen finally get together and become engaged . Keith also plans to adopt Lucas . Tragedy strikes when Lucas's former friend Jimmy Edwards brings a gun to school and fires it, accidentally hitting Peyton and causing a lockdown ("With Tired Eyes, Tired Minds, Tired Souls, We Slept"). Lucas saves Peyton and is devastated by Jimmy and Keith's eventual deaths . After seeing the effect of Keith's death on his mother, Lucas decides to finally tell Whitey, Nathan, and Karen about his heart condition and quits basketball . He goes on a university tour with his mother and realizes that he wants to become a writer . He is also Nathan's best man for his second wedding to Haley . He and Brooke break up for good during the wedding when Brooke learns that Lucas kissed Peyton back during the school shooting . </P> <P> In Season 4, Lucas tries to get Brooke back, but she rejects him, feeling that the passion is no longer there . One day, he hurries to save Peyton from Internet stalker "Psycho Derek", and becomes considerably closer to her afterward . He also helps Karen, who is pregnant with Keith's baby, and plans on going to the University of North Carolina when he graduates so that he can be close to home in case she needs him . Dan also helps Karen with her pregnancy, wanting to make amends for Keith's death . After talking with Dan, Karen persuades Whitey to let Lucas play 15 minutes a game, so as not to let him miss out on something he loves . Brooke and Lucas try dating each other again, but realize that it is not what they truly want and is not what is meant to be, prompting Peyton to confess her feelings for Lucas . Lucas then discovers that Nathan is planning to throw the state championship game because of his debts . Lucas plans to prevent this and deliberately fails to take his heart medication in order to play better, but Nathan is inspired by learning that he is going to have a son and they win, with Lucas making the winning shot . During the celebration, Lucas, after receiving Brooke's blessing, sees Peyton and tells her that she is the girl he has been meant for . The two then share a long - awaited kiss . They become a couple at the after - party, but their happiness is short - lived when Haley gets hit by a car and Lucas tries to tell the paramedics what happened only to suffer a heart attack . As he is in the hospital, Lucas dreams that he is visited by Keith, who shows Lucas what life would have been like if he had been a lesser person . In the end, Lucas realizes that he has to go back to his life because he never told Peyton that he loves her . Lucas wakes up and begins a relationship with Peyton . After the failed attempt of prom in Tree Hill High, the group go on a rescue mission to save Mouth who has become stranded in Honeygrove . They all then crash the local Prom, where he and Peyton have sex with each other for the first time . He begins to investigate Keith's death, as the Keith in his dream suggested that Jimmy did not kill him, but he also starts getting closer to Dan, who tells Karen he wants a bigger part in Lucas's life . Lucas discovers the truth about Dan thanks to witness Abby Brown . He attacks Dan after walking in on him and Karen kissing and tells Karen that Dan killed Keith, but Dan convinces Karen that Lucas is delusional and needs help . Lucas then steals Deb's gun and confronts Dan in front of Karen, having set him up by sending him a message from "Abby". Karen collapses and Lucas fires a warning shot at Dan, telling him not to touch her . Karen is rushed to hospital with eclampsia and has an emergency c - section . Lucas is given a half - sister, who is named Lily Roe Scott when Karen regains consciousness . Later, Dan turns himself in for Keith's murder . Lucas graduates and gets, as a reward, his book (An Unkindness of Ravens) from his mother . That same day, he becomes an uncle with the birth of Nathan and Haley's son, James Lucas Scott, partly named after him . Lucas is named the godfather of James and announces that he will be assisting Whitey as Nathan's college basketball coach . </P> <P> One year from Season 4, Lucas becomes the head coach of the Cobras, his college basketball team, and leads them to victory in the championships . Thinking about his future, he goes to see Peyton and asks her to marry him . She declines, feeling that it is too soon . As he is about to leave LA, his novel is picked up by a fresh new editor, Lindsey Strauss . It is a moment when his greatest dream came true . He is about to call Peyton, but decides against it, and instead calls Brooke . They spend a crazy evening together, and, in the end, he kisses her because he feels lonely . Although Brooke still loves him at the time, she pushes him away, remembering Peyton . Soon after, he is scheduled to have a book signing in LA where Peyton is living and working . Having missed her, he calls her and invites her to come to the signing . Peyton comes, but she witnesses Lindsey giving Lucas a congratulatory kiss and assumes they are in a relationship and leaves thinking there is no hope for her and Lucas . Lucas thinks that Peyton did not bother to come, and consequently begins dating Lindsey . </P>

When does lucas find out dan killed keith