<P> The philosopher's stone is created by the alchemical method known as The Magnum Opus or The Great Work . Often expressed as a series of color changes or chemical processes, the instructions for creating the philosopher's stone are varied . When expressed in colors, the work may pass through phases of nigredo, albedo, citrinitas, and rubedo . When expressed as a series of chemical processes it often includes seven or twelve stages concluding in multiplication, and projection . </P> <P> The philosopher's stone has been an inspiration, plot feature, or subject of innumerable artistic works: animations, comics, films, musical compositions, novels, and video games . </P>

Who created the philosopher's stone in fullmetal alchemist