<P> Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl - CoA by a process called pyruvate decarboxylation . Acetyl - CoA may then be used in the citric acid cycle to carry out cellular respiration, and this complex links the glycolysis metabolic pathway to the citric acid cycle . Pyruvate decarboxylation is also known as the "pyruvate dehydrogenase reaction" because it also involves the oxidation of pyruvate . </P> <P> This multi-enzyme complex is related structurally and functionally to the oxoglutarate dehydrogenase and branched - chain oxo - acid dehydrogenase multi-enzyme complexes . </P> <P> The reaction catalysed by pyruvate dehydrogenase complex is: </P> <Table> <Tr> <Td> pyruvate </Td> <Td_colspan="2"> pyruvate dehydrogenase complex </Td> <Td> acetyl CoA </Td> </Tr> <Tr> <Td> </Td> <Td_colspan="2"> </Td> <Td> </Td> </Tr> <Tr> <Td> CoA - SH + NAD </Td> <Td> CO + NADH + H </Td> </Tr> <Tr> <Td_colspan="2"> </Td> </Tr> <Tr> <Td> </Td> <Td> </Td> </Tr> <Tr> <Td_colspan="2"> </Td> </Tr> <Tr> <Td> </Td> <Td_colspan="2"> </Td> <Td> </Td> </Tr> </Table>

Where does pyruvate conversion to acetyl coa occur