<P> A palindromic sequence is a nucleic acid sequence on double - stranded DNA or RNA wherein reading 5' (five - prime) to 3' (three prime) forward on one strand matches the sequence reading 5' to 3' on the complementary strand with which it forms a double helix . This definition of palindrome thus depends on complementary strands being palindromic of each other . </P> <P> The meaning of palindrome in the context of genetics is slightly different from the definition used for words and sentences . Since a double helix is formed by two paired strands of nucleotides that run in opposite directions in the 5' - to - 3' sense, and the nucleotides always pair in the same way (Adenine (A) with Thymine (T) for DNA, with Uracil (U) for RNA; Cytosine (C) with Guanine (G)), a (single - stranded) nucleotide sequence is said to be a palindrome if it is equal to its reverse complement . For example, the DNA sequence ACCTAGGT is palindromic because its nucleotide - by - nucleotide complement is TGGATCCA, and reversing the order of the nucleotides in the complement gives the original sequence . </P> <P> A palindromic nucleotide sequence can form a hairpin . Palindromic DNA motifs are found in most genomes or sets of genetic instructions . Palindromic motifs are made by the order of the nucleotides that specify the complex chemicals (proteins) which, as a result of those genetic instructions, the cell is to produce . They have been specially researched in bacterial chromosomes and in the so - called Bacterial Interspersed Mosaic Elements (BIMEs) scattered over them . Recently, a research genome sequencing project discovered that large part of sequences on the Y and X chromosomes are arranged as palindromes . A palindrome structure allows the Y chromosome to repair itself by bending over at the middle if one side is damaged . </P>

All restriction sites are palindromic. what does this mean
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