<P> Ramirez's breakout role came when she was cast as the Lady of the Lake in Eric Idle and John Du Prez's musical Spamalot . Based on the 1975 film Monty Python and the Holy Grail, the musical opened on Broadway in 2005 to widespread acclaim . Ramirez in particular was singled out for her performance, winning several awards including the 2005 Tony Award for Best Featured Actress in a Musical and the Drama League Award for Distinguished Performance . Ben Brantley of The New York Times described her as "a toothsome devourer of scenery", while another reviewer for The Playgoer emphasizing on her stage presence remarked that, "her intensity is totally serious and totally ludicrous and totally on key". An Entertainment Weekly review gave her the highest praise by calling her a show - stealer . </P> <P> Following her success on Broadway, Ramirez joined the cast of Grey's Anatomy in a recurring role as Dr. Calliope' Callie' Torres, a love interest for Dr. George O'Malley, in the show's second season . On a special Grey's Anatomy - themed episode of The Oprah Winfrey Show, she revealed that top executives from ABC, who were greatly impressed by her performance in Spamalot, offered her a role in any ABC show she wanted . She picked Grey's, as she was already a fan of the show . Ramirez further explained that at her initial audition, the producers liked her, and had intentions to add her to the show, but did not know who to cast her as . She also said she was in awe of how the executives said, "Pick a show, any show", explaining that it is rare . The series creator and executive producer, Shonda Rhimes explained: "I was looking for a girlfriend for George, but it was in the infancy stages, so I had no idea what I was looking for ." Rhimes built the character around Ramirez after she met her . Ramirez, who was initially given a recurring status at the time of the character's inception, received a star billing in the show's third season, alongside fellow cast member Eric Dane, who portrayed Dr. Mark Sloan . </P> <P> Ramirez provided a cappella vocals in the song "Silent Night" for the soundtrack of the show's sixth season episode "Holidaze," airing on November 192009 . Ramirez's served as the main vocalist for the musical episode of Grey's Anatomy, "Song Beneath the Song", which on aired March 31, 2011 . Marcus James Dixon of Gold Derby calling her the "show - stopper", wrote, "stole the show in a gut - wrenching performance worthy of an Emmy award ." In May 2016, Ramirez left the show at the conclusion of the twelfth season, after having played the character for a decade . She released a statement saying, "I'm deeply grateful to have spent the last 10 years with my family at Grey's Anatomy and ABC, but for now I'm taking some welcome time off". </P> <P> As the series progressed, th character's popularity soared and Ramirez garnered widespread recognition and critical acclaim for her portrayal of a complex character on television . Reviewing the performances of Ramirez and Jessica Capshaw an episode of the eleventh season, Maggie Fremont of Vulture called them, "goddesses walking amongst mere mortals". Rhimes wrote of Ramirez's work on the show: "Dr. Callie Torres came into our lives dancing it out in her underwear almost a decade ago, and I could not be happier or more proud of her journey . Sara Ramirez's performance inspired me as well as millions of fans each week ." Ramirez was nominated for Outstanding Actress in a Drama Television Series at the Alma Awards, in 2007 and 2008 . Also in 2007, at the 13th Screen Actors Guild Awards, the cast of Grey's Anatomy, were the recipients of the Award for Outstanding Performance by an Ensemble in a Drama Series . She and the cast were nominated for the same award, in 2008 . In 2011, at the 42nd NAACP Image Awards, Ramirez was nominated for Outstanding Supporting Actress in a Drama Series . </P>

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