<P> An example is the teratogen and carcinogen phorbol 12 - myristate 13 - acetate, which is a plant terpene that activates protein kinase C, which promotes cancer, making it a useful investigative tool . There is also interest in creating small molecule artificial transcription factors to regulate gene expression, examples include wrenchnolol (a wrench shaped molecule). </P> <P> Binding of ligand can be characterised using a variety of analytical techniques such as surface plasmon resonance, microscale thermophoresis or dual polarisation interferometry to quantify the reaction affinities and kinetic properties and also any induced conformational changes . </P> <P> Small - molecule anti-genomic therapeutics, or SMAT, refers to a biodefense technology that targets DNA signatures found in many biological warfare agents . SMATs are new, broad - spectrum drugs that unify antibacterial, antiviral and anti-malarial activities into a single therapeutic that offers substantial cost benefits and logistic advantages for physicians and the military . </P>

What is the difference between a large molecule and a small molecule