<Table> <Tr> <Td_colspan="2"> View / Edit Human </Td> <Td_colspan="2"> View / Edit Mouse </Td> </Tr> </Table> <Tr> <Td_colspan="2"> View / Edit Human </Td> <Td_colspan="2"> View / Edit Mouse </Td> </Tr> <P> Ghrelin (pronounced / ˈɡrɛlɪn /), the "hunger hormone", also known as lenomorelin (INN), is a peptide hormone produced by ghrelinergic cells in the gastrointestinal tract which functions as a neuropeptide in the central nervous system . Besides regulating appetite, ghrelin also plays a significant role in regulating the distribution and rate of use of energy . </P> <P> When the stomach is empty, ghrelin is absorbed . When the stomach is stretched, secretion stops . It acts on hypothalamic brain cells both to increase hunger, and to increase gastric acid secretion and gastrointestinal motility to prepare the body for food intake . </P>

Which hormone plays a significant role in appetite stimulation