<P> In 2000--2001, Davis starred in the short - lived sitcom The Geena Davis Show . In the beginning of 2004, she guest - starred as Grace Adler's sister, Janet, on the NBC sitcom Will & Grace . She went on to star in the ABC television series Commander in Chief, portraying the first female president of the United States . This role garnered her a Golden Globe for Best Actress in a Drama Series in 2006, and she also was nominated for an Emmy Award and a SAG Award for Outstanding Female Actor in a Drama Series . Also in 2006, she was awarded the Women in Film Lucy Award . </P> <P> She starred in the Australian - produced, American - set Accidents Happen, which was released in April 2010 . </P> <P> During the 11th season of Grey's Anatomy, Davis played a recurring role as Dr. Nicole Herman, who is an attending fetal surgeon who has a life - threatening brain tumor . </P> <P> In October 2015, it was announced that Davis would be starring in the film adaptation of Marjorie Prime alongside Jon Hamm . </P>

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