<Li> Key: UZHSEJADLWPNLE - GRGSLBFTSA - N </Li> <Tr> <Th_colspan="2"> (what is this?) (verify) </Th> </Tr> <P> Naloxone, sold under the brandname Narcan among others, is a medication used to block the effects of opioids, especially in overdose . Naloxone may be combined within the same pill as an opioid to decrease the risk of misuse . When given intravenously, naloxone works within two minutes, and when injected into a muscle, it works within five minutes; it may also be sprayed into the nose . The effects of naloxone last about half an hour to an hour . Multiple doses may be required, as the duration of action of most opioids is greater than that of naloxone . </P> <P> Administration to opioid - dependent individuals may cause symptoms of opioid withdrawal, including restlessness, agitation, nausea, vomiting, a fast heart rate, and sweating . To prevent this, small doses every few minutes can be given until the desired effect is reached . In those with previous heart disease or taking medications that negatively affect the heart, further heart problems have occurred . It appears to be safe in pregnancy, after having been given to a limited number of women . Naloxone is a pure opioid antagonist . It works by reversing the depression of the central nervous system and respiratory system caused by opioids . </P>

Is narcan used for anything other than overdose