<Tr> <Th> MedlinePlus </Th> <Td> 003003 </Td> </Tr> <Tr> <Td_colspan="2"> (edit on Wikidata) </Td> </Tr> <P> A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end - stage heart failure or severe coronary artery disease when other medical or surgical treatments have failed . As of 2016, the most common procedure is to take a functioning heart, with or without transplanting one or both lungs at the same time, from a recently deceased organ donor (brain death is the standard) and implanting it into the patient . The patient's own heart is either removed and replaced with the donor heart (orthotopic procedure) or, much less commonly, the recipient's diseased heart is left in place to support the donor heart (heterotopic, or "piggyback," transplant procedure). Approximately 3500 heart transplants are performed every year in the world, more than half of which occur in the US . Post-operation survival periods average 15 years . Heart transplantation is not considered to be a cure for heart disease, but a life - saving treatment intended to improve the quality of life for recipients . </P> <P> One of the first mentions of the possibility of heart transplantation was by American medical researcher Simon Flexner, who declared in a reading of his paper on "Tendencies in Pathology" in the University of Chicago in 1907 that it would be possible in the then - future for diseased human organs substitution for healthy ones by surgery--including arteries, stomach, kidneys and heart . </P>

Where do hearts come from for heart transplants