<Tr> <Th> Frequency </Th> <Td> 6 per 100,000 people </Td> </Tr> <Tr> <Td_colspan="2"> (edit on Wikidata) </Td> </Tr> <P> Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed . The initial symptom is typically enlargement of the hands and feet . There may also be enlargement of the forehead, jaw, and nose . Other symptoms may include joint pain, thicker skin, deepening of the voice, headaches, and problems with vision . Complications of the disease may include type 2 diabetes, sleep apnea, and high blood pressure . </P> <P> Acromegaly is typically due to the pituitary gland producing too much growth hormone . In more than 95% of cases the excess production is due to a benign tumor, known as a pituitary adenoma . The condition is not inherited from a person's parents . Rarely acromegaly is due to tumors in other parts of the body . Diagnosis is by measuring growth hormone after a person has drunk glucose or by measuring insulin - like growth factor I in the blood . After diagnosis, medical imaging of the pituitary is carried out to look for an adenoma . If excess growth hormone is produced during childhood the result is gigantism . </P>

Acromegly is a disorder due to chronically high levels of