<Tr> <Th> Frequency </Th> <Td> 3 per 100,000 per year (developed world) </Td> </Tr> <P> Toxic shock syndrome (TSS) is a condition caused by bacterial toxins . Symptoms may include fever, rash, skin peeling, and low blood pressure . There may also be symptoms related to the specific underlying infection such as mastitis, osteomyelitis, necrotising fasciitis, or pneumonia . </P> <P> TSS is caused by bacteria of either the Streptococcus pyogenes or Staphylococcus aureus type . Streptococcal toxic shock syndrome (STSS) is sometimes referred to as toxic shock - like syndrome (TSLS). The underlying mechanism involves the production of superantigens during an invasive streptococcus infection or a localized staphylococcus infection . Risk factors for the staphylococcal type include the use of very absorbent tampons and skin lesions in young children . Diagnosis is typically based on symptoms . </P> <P> Treatment includes antibiotics, incision and drainage of any abscesses, and possibly intravenous immunoglobulin . The need for rapid removal of infected tissue via surgery in those with a streptococcal cause, while commonly recommended, is poorly supported by the evidence . Some recommend delaying surgical debridement . The overall risk of death in streptococcal disease is about 50% while in staphylococcal disease it is around 5% . Death may occur within 2 days . </P>

How does staphylococcus aureus cause toxic shock syndrome
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