<Dl> <Dd> 1 pg = 978 Mb (\ displaystyle 1 (\ text (pg)) = 978 (\ text (Mb))) </Dd> </Dl> <Dd> 1 pg = 978 Mb (\ displaystyle 1 (\ text (pg)) = 978 (\ text (Mb))) </Dd> <P> In 1991, John W. Drake proposed a rule: that the mutation rate within a genome and its size were inversely correlated . This rule has been found to be approximately correct for DNA viruses and unicellular organisms . Its basis is unknown . </P> <P> The small size of RNA viruses has been proposed to be locked into a three part relation between replication fidelity, genome size and genetic complexity . The majority of RNA viruses lack an RNA proofreading facility which limits their replication fidelity and hence the genome size . This has also been described as the Eigen paradox . </P>

How does the e. coli genome size compare to that of humans