<P> Resistant starch from high - amylose corn, amylomaize, has been shown to reduce insulin resistance in healthy individuals, in individuals with insulin resistance, and in individuals with type 2 diabetes . Animal studies demonstrate that it cannot reverse damage already done by high glucose levels, but that it reduces insulin resistance and reduces the development of further damage . </P> <P> Some types of polyunsaturated fatty acids (omega - 3) may moderate the progression of insulin resistance into type 2 diabetes, however, omega - 3 fatty acids appear to have limited ability to reverse insulin resistance, and they cease to be efficacious once type 2 diabetes is established . </P> <P> Caffeine intake limits insulin action, but not enough to increase blood - sugar levels in healthy persons . People who already have type 2 diabetes may see a small increase in levels if they take 2 or 2 - 1 / 2 cups of coffee per day . </P> <P> The concept that insulin resistance may be the underlying cause of diabetes mellitus type 2 was first advanced by Professor Wilhelm Falta and published in Vienna in 1931, and confirmed as contributory by Sir Harold Percival Himsworth of the University College Hospital Medical Centre in London in 1936, however, type 2 diabetes does not occur unless there is concurrent failure of compensatory insulin secretion . </P>

What is the major cause of insulin resistance